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Critical protein prevents DNA damage from persisting through generations

Critical protein prevents DNA damage from persisting through generations

Biology /

created Jun 29, 2007 | popularity 4.1 / 5 (9) | comments 0

A protein long known to be involved in protecting a cell from genetic damage has been found to play an even more important role in protecting the cell’s offspring. New research shows that the protein, known ...


Landmark study sheds new light on human chromosomal birth defects

Landmark study sheds new light on human chromosomal birth defects

Biology / Cell & Microbiology

created Sep 16, 2009 | popularity 4.8 / 5 (4) | comments 0

Using yeast genetics and a novel scheme to selectively remove a single protein from the cell division process called meiosis, a cell biologist at The Florida State University found that when a key molecular ...


Researchers identify key mechanism that occurs at the inception point of many human lymphomas

Biology /

created Dec 11, 2008 | popularity 5 / 5 (2) | comments 1

Researchers at the Keck School of Medicine of the University of Southern California (USC) have explained how certain key mutations occur in human lymphomas—a process that has, until now, remained a mystery.


Researchers identify potential cancer target

Researchers identify potential cancer target

Medicine & Health / Cancer

created Jan 16, 2009 | popularity 5 / 5 (1) | comments 1

(PhysOrg.com) -- Dartmouth Medical School researchers have found two proteins that work in concert to ensure proper chromosome segregation during cell division. Their study is in the January 2009 issue of ...


Cohesin jigsaw begins to fit

Biology / Cell & Microbiology

created May 19, 2009 | popularity 5 / 5 (1) | comments 0

The essential chromosomal protein complex cohesin has crucial roles in sister chromatid cohesion, DNA repair and transcriptional regulation. Despite its conserved function, cohesin's disparate association patterns in different ...


Prenatal biochemical screening only detects half of chromosomal abnormalities

Medicine & Health / Genetics

created Jun 02, 2008 | popularity not rated yet | comments 0

Prenatal biochemical screening tests are widely used to look for chromosomal abnormalities in the fetus which can lead to serious handicap, or even death during gestation or in the first few days after birth. But these tests ...


Once suspect protein found to promote DNA repair, prevent cancer

Medicine & Health / Research

created Jul 21, 2008 | popularity 5 / 5 (3) | comments 0

An abundant chromosomal protein that binds to damaged DNA prevents cancer development by enhancing DNA repair, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Proceedings of ...


Protein plays unexpected role protecting chromosome tips

Protein plays unexpected role protecting chromosome tips

Biology / Cell & Microbiology

created Aug 13, 2009 | popularity 5 / 5 (2) | comments 0

A protein specialist that opens the genomic door for DNA repair and gene expression also turns out to be a multi-tasking workhorse that protects the tips of chromosomes and dabbles in a protein-destruction ...


Ultrasound enhances noninvasive Down syndrome tests

Medicine & Health / Diseases

created Nov 20, 2009 | popularity not rated yet | comments 0

The addition of a "genetic sonogram" maximizes the accuracy of non-invasive testing for Down syndrome, said a Baylor College of Medicine researcher who was lead author of a landmark study in the current issue of Obstetrics an ...


Experienced pilots may be at risk of DNA damage from ionizing radiation

Medicine & Health / Other

created Dec 11, 2008 | popularity 4.5 / 5 (2) | comments 0

Airline pilots who have flown for many years may be at risk of DNA damage from prolonged exposure to cosmic ionising radiation, suggests a study published ahead of print in Occupational and Environmental Medicine.


Researchers identify novel mechanism for regulation of gene expression

Biology /

created Sep 26, 2008 | popularity 3.8 / 5 (4) | comments 0

The Stowers Institute's Conaway Lab has demonstrated that an enzyme called Uch37 is kept in check when it is part of a human chromatin remodeling complex, INO80. The results were published in today's issue of Molecular Ce ...


Scientists demonstrate role of protein in distinguishing chromosome ends from DNA breaks

Medicine & Health / Cancer

created Sep 17, 2009 | popularity not rated yet | comments 0

The Stowers Institute's Baumann Lab has demonstrated how human cells protect chromosome ends from misguided repairs that can lead to cancer. The work, published in The EMBO Journal, a publication of the European Molecular Biolog ...


New technique detects specific chromosomal damage, may indicate lung cancer risk

Medicine & Health / Cancer

created Aug 31, 2007 | popularity 4.7 / 5 (3) | comments 0

A new technique could pave the way toward screening people at risk for lung cancer for the genetic changes that may foreshadow malignancies, researchers from the University of Colorado say.


Photonic crystal biosensors detect protein-DNA interactions

Biology /

created Sep 23, 2008 | popularity 5 / 5 (6) | comments 0

Scientists at the University of Illinois have developed a new class of disposable, microplate-based optical biosensors capable of detecting protein-DNA interactions. Based on the properties of photonic crystals, the biosensors ...


Novel chromosome abnormality appears to increase risk of autism

Medicine & Health / Diseases

created Jan 09, 2008 | popularity 3.5 / 5 (2) | comments 0

A multi-institutional study involving Massachusetts General Hospital (MGH) researchers has identified a chromosomal abnormality that appears to increase susceptibility to autism. In a New England Journal of Medicine report ...