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Scientists probe mechanism of asymmetry in meiotic cell division

Biology /

created Oct 07, 2008 | popularity 4.3 / 5 (3) | comments 0

The Stowers Institute's Rong Li Lab has characterized a mechanism that allows for asymmetrical cell division during meiosis in oocytes. By tracking chromosome movement in live mouse oocytes, the team discovered that chromosomes ...


Scientists demonstrate role of protein in distinguishing chromosome ends from DNA breaks

Medicine & Health / Cancer

created Sep 17, 2009 | popularity not rated yet | comments 0

The Stowers Institute's Baumann Lab has demonstrated how human cells protect chromosome ends from misguided repairs that can lead to cancer. The work, published in The EMBO Journal, a publication of the European Molecular Biolog ...


Researchers characterize novel regulator of chromosome function

Biology /

created Mar 10, 2008 | popularity not rated yet | comments 0

The Stowers Institute's Workman Lab has shed new light on a novel histone acetyltransferase protein complex called ATAC. Acetyltransferases are enzymes that introduce a new acetyl functional group into histone proteins, a ...


Male sex chromosome losing genes by rapid evolution, study reveals

Male sex chromosome losing genes by rapid evolution, study reveals

Biology / Evolution

created Jul 17, 2009 | popularity 4.1 / 5 (15) | comments 11

Scientists have long suspected that the sex chromosome that only males carry is deteriorating and could disappear entirely within a few million years, but until now, no one has understood the evolutionary ...


Sex Talk Revelations of the Lonely Y Chromosome

Medicine & Health / Genetics

created Sep 09, 2009 | popularity 4.3 / 5 (3) | comments 3

(PhysOrg.com) -- In the week that the University of Leicester celebrates the 25th anniversary of the discovery of DNA fingerprinting (Thursday September 10) new findings from the world-renowned University of Leicester Department ...


'Achilles' heel' in Y chromosome linked to sex disorders

'Achilles' heel' in Y chromosome linked to sex disorders

Medicine & Health / Research

created Sep 03, 2009 | popularity not rated yet | comments 0

The unique mechanism behind the evolutionary survival of the human Y chromosome may also be responsible for a range of sex disorders, from failed sperm production to sex reversal to Turner Syndrome.


Researchers discover mechanism that prevents two species from reproducing

Biology / Biotechnology

created Oct 26, 2009 | popularity 5 / 5 (6) | comments 3

Cornell researchers have discovered a genetic mechanism in fruit flies that prevents two closely related species from reproducing, a finding that offers clues to how species evolve.


New study rewrites textbook on key genetic phenomenon

Medicine & Health / Genetics

created Jul 01, 2009 | popularity 4 / 5 (2) | comments 1

Because females carry two copies of the X chromosome to males' one X and one Y, they harbor a potentially toxic double dose of the over 1000 genes that reside on the X chromosome.


Dartmouth researchers find new protein function

Dartmouth researchers find new protein function

Biology /

created Jan 09, 2009 | popularity 4 / 5 (1) | comments 0

A group of Dartmouth researchers has found a new function for one of the proteins involved with chromosome segregation during cell division. Their finding adds to the growing knowledge about the fundamental ...


Double success for Instituto Gulbenkian de Ciencia scientists working on chromosome segregation

Portuguese scientists working on chromosome segregation

Biology / Cell & Microbiology

created Jul 01, 2009 | popularity not rated yet | comments 0

Lars Jansen's work on the formation of the centromere, a key cellular structure in powering and controlling chromosome segregation and accurate cell division, has just earned him a paper in Nature Cell Bi ...


Molecule Tracking Reveals Mechanism of Chromosome Separation in Dividing Cells

Single molecule tracking helps reveal mechanism of chromosome separation in dividing cells

Biology / Cell & Microbiology

created Mar 06, 2009 | popularity 5 / 5 (3) | comments 1

(PhysOrg.com) -- University of Washington (UW) researchers are helping to write the operating manual for the nano-scale machine that separates chromosomes before cell division. The apparatus is called a spindle ...


How cells handle broken chromosomes

Chemistry /

created Feb 13, 2009 | popularity 4.5 / 5 (2) | comments 0

(PhysOrg.com) -- After being recognized and initially processed by the cellular machinery, the broken chromosome is extensively scanned for homology and the break itself is later tethered to the nuclear envelope. Thus the ...


Amount of gene surplus determines severity of mental retardation in males

Medicine & Health / Genetics

created Dec 10, 2009 | popularity 5 / 5 (1) | comments 0

Researchers have discovered a new explanation for differences in the severity of mental illness in males. The more excess copies of a certain gene, the more serious the handicap. The genetic defect is situated on the X-chromosome; ...


Dogs, humans, put heads together to find cure for brain cancer

Medicine & Health / Genetics

created Jul 06, 2009 | popularity not rated yet | comments 0

Pinpointing the genes involved in human brain cancer can be like looking for a needle in a haystack, and sometimes the needle you find may not be the right one. By comparing human and canine genomes, researchers at North ...


Novel genetic region identified for childhood asthma in Mexicans

Medicine & Health / Genetics

created Aug 28, 2009 | popularity 5 / 5 (1) | comments 0

Genetic variants in a region on chromosome 9q may influence asthma development in Mexican children, according to research published in the August 28 issue of the open-access journal PLoS Genetics.