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Scientists make headway in understanding Alzheimer's disease

Medicine & Health / Research

created Feb 05, 2009 | popularity 4.6 / 5 (5) | comments 0

Scientists at UC Santa Barbara have discovered that a protein called BAG2 is important for understanding Alzheimer's disease and may open up new targets for drug discovery. They are ready to move from studying ...


Biologists discover bacterial defense mechanism against aggressive oxygen

Biology / Cell & Microbiology

created Nov 20, 2009 | popularity not rated yet | comments 0

Bacteria possess an ingenious mechanism for preventing oxygen from harming the building blocks of the cell. This is the new finding of a team of biologists that includes Joris Messens of VIB, a life sciences research institute ...


New study bolsters beliefs about DNA repair

Biology /

created Nov 17, 2008 | popularity 4.3 / 5 (3) | comments 0

Aucott et al. report the first in vivo experiments on the heterochromatin protein 1 (HP1) family, which sidles up to silent DNA. The results, to be published in the Nov. 17 issue of the Journal of Cell Biology, add to the ...


Researchers give mutants another chance

Chemistry /

created Feb 11, 2009 | popularity 5 / 5 (2) | comments 0

Researchers at Fox Chase Cancer Center have demonstrated that it might be possible to treat genetic diseases, including some forms of cancer, by "rescuing" the misshapen, useless proteins produced by some mutant genes.


New activity found for a potential anti-cancer agent

Chemistry / Biochemistry

created Nov 02, 2009 | popularity not rated yet | comments 0

Pateamine A (PatA), a natural product first isolated from marine sponges, has attracted considerable attention as a potential anti-cancer agent, and now a new activity has been found for it, which may reveal yet another anti-cancer ...


Discovery Links Proteins Necessary to Repair Membranes

Chemistry / Biochemistry

created Jun 11, 2009 | popularity 5 / 5 (3) | comments 0

(PhysOrg.com) -- Researchers at UMDNJ-Robert Wood Johnson Medical School are a step closer to treating, and perhaps preventing, muscle damage caused by disease and aging. In their study, published in the June issue of Journal of ...


Short bacterial protein is surprisingly versatile

Biology /

created Jan 18, 2008 | popularity 4.3 / 5 (3) | comments 0

MIT researchers have discovered why an unusually short bacterial protein can have many more interactions than would normally be expected of something its size.


New discovery linked to DNA repair and cancer

New discovery linked to DNA repair and cancer

Medicine & Health / Genetics

created May 01, 2008 | popularity 4.6 / 5 (7) | comments 0

Scientists have discovered a new protein in humans that plays an important role in repairing DNA damage that could lead to cancer.


Misfolded proteins: The fundamental problem is aging

Biology / Cell & Microbiology

created Aug 24, 2009 | popularity 4.4 / 5 (9) | comments 2

Proteins are essential for all biological activities and the health of the cell. Misfolded and damaged proteins spell trouble and are common to all human neurodegenerative diseases and many other age-associated diseases. ...


DNA-damaged cells communicate with neighbors to let them know they're in trouble

Biology / Cell & Microbiology

created Jul 13, 2009 | popularity not rated yet | comments 0

When cells experiencing DNA damage fail to repair themselves, they send a signal to their neighbors letting them know they're in trouble. The discovery, which shows that a process dubbed the DDR (DNA Damage Response) also ...


Scientists determine 3D structure of proteins in living cells for the first time

Biology / Cell & Microbiology

created Mar 05, 2009 | popularity 5 / 5 (4) | comments 0

(PhysOrg.com) -- A University of Glasgow scientist was part of a team of researchers which has, for the first time, been able to determine the three-dimensional structure of protein in living cells.


Scientists develop tool to probe role of oxidative stress in aging, disease

Medicine & Health / Research

created Feb 15, 2008 | popularity 3.7 / 5 (7) | comments 0

Oxygen, although essential for human life, can turn into an aggressive chemical that is outright toxic to important molecules inside our cells. This "oxidative stress" is associated with many diseases, such as Alzheimer's, ...


Raising the alarm when DNA goes bad (w/ Video)

Biology / Cell & Microbiology

created Aug 13, 2009 | popularity 2 / 5 (1) | comments 1

Scientists have known for a long time that when DNA is damaged, a key enzyme sets off a cellular "alarm bell" to alert the cell to start the repair process, but until recently little was known about how the cell detects and ...


Refusal of suicide order: Why tumor cells become resistant

Medicine & Health / Other

created Jun 23, 2008 | popularity 4.5 / 5 (2) | comments 1

Cells with irreparable DNA damage normally induce programmed cell death, or apoptosis. However, this mechanism often fails in tumor cells so that transformed cells are able to multiply and spread throughout the body. Scientists ...


Researches identify herpesvirus proteins that target key cellular processes

Medicine & Health / Diseases

created Jul 11, 2008 | popularity 4.5 / 5 (2) | comments 0

A study published July 11th in the open-access journal PLoS Pathogens suggests that herpesviruses use multiple strategies to manipulate important components of the host cell nuclear environment during infection. The study, ...