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Search results for death domain
Researchers discover 'on switch' for cell death signaling mechanism
Biology /
Jan 05, 2009 |
4.5 / 5 (6) |
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Scientists at Burnham Institute for Medical Research (Burnham) have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for ...
A tricky tumor virus
Jan 17, 2008 |
4.7 / 5 (3) |
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Epstein-Barr virus (EBV) is a human-pathogenic virus which belongs to the herpes virus family. Almost every adult carries EBV inside. With an infestation rate of more than 90 %, EBV is one of the most successful human viruses. ...
Protein that promotes cancer cell growth identified
Jul 24, 2009 |
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Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer ...
Researchers solve 'bloodcurdling' mystery
Jun 04, 2009 |
4.7 / 5 (3) |
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By applying cutting-edge techniques in single-molecule manipulation, researchers at Harvard University have uncovered a fundamental feedback mechanism that the body uses to regulate the clotting of blood. The finding, which ...
Researchers probe a DNA repair enzyme
Feb 18, 2008 |
4.7 / 5 (6) |
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Researchers have taken the first steps toward understanding how an enzyme repairs DNA. Enzymes called helicases play a key role in human health, according to Maria Spies, a University of Illinois biochemistry ...
Researchers solve structure of NMDA receptor unit that could be drug target for neurological diseases
Nov 12, 2009 |
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A team of scientists at Cold Spring Harbor Laboratory reports on Thursday their success in solving the molecular structure of a key portion of a cellular receptor implicated in Alzheimer's, Parkinson's, and other serious ...
By amplifying cell death signals, scientists make precancerous cells self-destruct
Aug 15, 2008 |
4.6 / 5 (17) |
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When a cell begins to multiply in a dangerously abnormal way, a series of death signals trigger it to self-destruct before it turns cancerous. Now, in research to appear in the August 15 issue of Genes & Development, Rockef ...
How Botulism Paralyzes Nerve Cells: New Details Revealed
Jun 22, 2009 |
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(PhysOrg.com) -- New structures of a botulism toxin interacting with a mimic of the nerve-cell protein it destroys suggest new ways to block this often-fatal interaction. Indeed, the mimic molecules have such ...
Sleep deprivation negatively affects split-second decision making, study shows
Nov 16, 2009 |
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Sleep deprivation adversely affects automatic, accurate responses and can lead to potentially devastating errors, a finding of particular concern among firefighters, police officers, soldiers and others who work in a sleep-deprived ...
Jackson's death unleashes barrage of online scams
Jun 30, 2009 |
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(AP) -- Minutes after any big celebrity dies, Internet swindlers get to work. They pump out specially created spam e-mails and throw up malicious Web sites to infect victims' computers, hoping to capitalize on the sudden ...
Shooter's online rants were like trees in forest
Aug 06, 2009 |
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(AP) -- In hindsight, it seems so obvious. We look back at the creepy online ramblings of a tortured soul like George Sodini and realize we should have known all along of the horrors to come.
Small molecules block cancer gene
Mar 10, 2009 |
5 / 5 (1) |
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Finding molecules that block the activity of the oncogene Stat 3 (signal transducer and activator of transcription) required screening literally millions of compounds, using computers that compared the structure of the cancer-causing ...
Scientists identify new regulatory mechanism for critical protein signaling domain
Biology /
Apr 05, 2007 |
5 / 5 (2) |
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In a study with far-reaching implications, scientists at the Scripps Research Institute and other institutions have for the first time identified a new in vivo regulatory mechanism for the PH Domain, a component of many proteins ...
Probing Question: Is the death penalty on the decline in America?
Other Sciences / Social Sciences
Dec 17, 2009 |
5 / 5 (1) |
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In November, the Commonwealth of Virginia executed John A. Muhammad, the infamous “D.C. sniper” responsible for 10 murders seven years earlier. On the eve of his execution, a Washington Post poll found 66 ...
Breaking down Huntington's disease one protein at a time
Biology /
Feb 04, 2008 |
5 / 5 (2) |
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Hoping to piece together the intricate series of interactions that lead to Huntington's disease, Indiana University Bloomington scientists have determined the shape and structure of a binding site that may ...
