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Researchers discover pathway with implications for obesity

Researchers discover pathway with implications for obesity

Medicine & Health / Research

created Jun 03, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Cornell scientists have discovered how two related proteins and their roles in a key molecular pathway are critical to creating obesity-causing fat cells.


Legionnaire's bacterial proteins work together to survive

Biology /

created Oct 23, 2007 | popularity 4.5 / 5 (2) | comments 0

Proteins within the bacteria that cause Legionnaire’s disease can kidnap their own molecular “coffin” and carry it to a safe place within the cell, ensuring their survival, Yale School of Medicine researchers report in Nature Wednes ...


New gene that helps plants beat the heat

Biology /

created Oct 07, 2008 | popularity 4.6 / 5 (8) | comments 3

Michigan State University plant scientists have discovered another piece of the genetic puzzle that controls how plants respond to high temperatures. That may allow plant breeders to create new varieties of crops that flourish ...


Mutant CTRC gene has a new way to trigger pancreatitis

Medicine & Health / Research

created Dec 22, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- The CTRC gene is a lot like your baby brother—mutant and annoying. Drs. Miklos Sahin-Toth and Richard Szmola of the Department of Molecular & Cell Biology at Boston University Henry M. Goldman School of Dental ...


Animal study suggests inadequate sleep may exacerbate cellular aging in the elderly

Medicine & Health / Other

created Jun 27, 2008 | popularity 5 / 5 (1) | comments 0

Researchers at the University of Pennsylvania School of Medicine have shown that the unfolded protein response, which is a reaction to stress induced by sleep deprivation, is impaired in the brains of old mice.


Visualizing virus replication in three dimensions

Visualizing virus replication in three dimensions

Biology / Cell & Microbiology

created May 07, 2009 | popularity 5 / 5 (1) | comments 0

Dengue fever is the most common infectious disease transmitted by mosquitoes - some 100 million people around the world are infected. Researchers at the Hygiene Institute at Heidelberg University Hospital ...


Not all fat is created equal

Medicine & Health / Diseases

created Aug 27, 2008 | popularity 4.6 / 5 (5) | comments 0

A Temple University study finds fat in obese patients is "sick" when compared to fat in lean patients.


Key protein may explain the anti-aging and anti-cancer benefits of dietary restriction

Medicine & Health / Genetics

created May 22, 2009 | popularity 4.7 / 5 (9) | comments 3

A protein that plays a key role in tumor formation, oxygen metabolism and inflammation is involved in a pathway that extends lifespan by dietary restriction. The finding, which appears in the May 22, 2009 edition of the ...


How Toxoplasma gondii gets noticed

Medicine & Health / Research

created Jan 19, 2009 | popularity not rated yet | comments 0

Researchers provide insight into how Toxoplasma gondii, a common parasite of people and other animals, triggers an immune response in its host. The report will appear online on January 19th in The Journal of Experimental Medicine. ...


Discovery of gene mechanism could bring about new ways to treat metastatic cancer

Medicine & Health / Cancer

created Jul 01, 2008 | popularity 4.9 / 5 (8) | comments 1

Virginia Commonwealth University and VCU Massey Cancer Center researchers have uncovered how a gene, melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24), induces a bystander effect that kills cancer cells ...


Saving the single cysteine: new antioxidant system found (w/ Video)

Chemistry / Biochemistry

created Nov 19, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- We've all read studies about the health benefits of having a life partner. The same thing is true at the molecular level, where amino acids known as cysteines are much more vulnerable to damage when single ...


Researchers identify missing target for calcium signaling

Medicine & Health / Neuroscience

created Apr 22, 2009 | popularity 5 / 5 (1) | comments 0

An international study led by Ohio State University neuroscience researchers describes one of the missing triggers that controls calcium inside cells, a process important for muscle contraction, nerve-cell transmission, insulin ...


Seeing Red

Unfolded proteins may protect cells from dying

Medicine & Health / Research

created Dec 26, 2006 | popularity 4 / 5 (3) | comments 0

When cells get stressed, their proteins go unfolded. It's a reaction with a straightforward name: the unfolded protein response. Now, new research from Rockefeller University shows that this phenomenon actually ...


Function of a neglected structure in neurons revealed after 50 years

Function of a neglected structure in neurons revealed after 50 years

Medicine & Health / Research

created Sep 08, 2009 | popularity 5 / 5 (12) | comments 4

(PhysOrg.com) -- Fifty years after it was originally discovered, scientists at the Friedrich Miescher Institute for Biomedical Research, Switzerland, have elucidated the function of a microscopic network of ...


Little-known protein found to be key player

Little-known protein found to be key player

Chemistry / Biochemistry

created Jul 29, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- Italian and U.S. biologists this week report that a little-understood protein previously implicated in a rare genetic disorder plays an unexpected and critical role in building and maintaining ...