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Major advance in cell reprogramming technology

Biology / Cell & Microbiology

created Apr 23, 2009 | popularity not rated yet | comments 0

In a paper publishing online April 23rd in Cell Stem Cell, a Cell Press journal, Dr. Sheng Ding and colleagues from the Scripps Research Institute in La Jolla, California, report an important step forward in the race to mak ...


New method for creating inducible stem cells is remarkably efficient

Biology /

created Sep 10, 2008 | popularity 4.5 / 5 (2) | comments 0

Some of the most challenging obstacles limiting the reprogramming of mature human cells into stem cells may not seem quite as daunting in the near future. Two independent research papers, published by Cell Press in the September ...


New technique produces genetically identical stem cells

Biology /

created Jul 01, 2008 | popularity 4.7 / 5 (11) | comments 0

Adult cells of mice created from genetically reprogrammed cells—so-called induced pluripotent stem (IPS) stem cells—can be triggered via drug to enter an embryonic-stem-cell-like state, without the need for further genetic ...


Reprogramming a patient's eye cells may herald new treatments against degenerative disease

Biology / Biotechnology

created Oct 22, 2009 | popularity 5 / 5 (3) | comments 1

Scientists have overcome a key barrier to the clinical use of stem cells with a technique which transforms regular body cells into artificial stem cells without the need for introducing foreign genetic materials, which could ...


Scientists identify compounds for stem-cell production from adult cells

Biology /

created Nov 05, 2008 | popularity 5 / 5 (2) | comments 0

In the study, the scientists screened known drugs and identified small molecules that could replace conventional reprogramming genes, which can have dangerous side effects. This new process offers a new way to generate stem ...


Scientists excise vector, exotic genes from induced stem cells

Biology / Cell & Microbiology

created Mar 26, 2009 | popularity 5 / 5 (5) | comments 0

A team of University of Wisconsin-Madison researchers reports that it has created induced human pluripotent stem (iPS) cells completely free of viral vectors and exotic genes.


Researchers piggyback to safer reprogrammed stem cells

Biology / Cell & Microbiology

created Feb 27, 2009 | popularity 5 / 5 (1) | comments 0

Austin Smith and his research team at the Centre for Stem Cell Research in Cambridge have just published in the journal Development a new and safer way of generating pluripotent stem cells - the stem cells that can give r ...


Converting adult somatic cells to pluripotent stem cells using a single virus

Biology /

created Jan 07, 2009 | popularity not rated yet | comments 0

A Boston University School of Medicine-led research team has discovered a more efficient way to create induced Pluripotent Stem (iPS) cells, derived from mouse fibroblasts, by using a single virus vector instead of multiple ...


Biologists find stem cell-like functions in other types of plant cells

Biology /

created Jan 28, 2009 | popularity 5 / 5 (2) | comments 0

Ordinary cells have the ability to replace lost organs in plants—a function previously thought to be limited to stem cells—researchers at New York University's Center for Genomics and Systems Biology and Utrecht University ...


Umbilical cord blood as a readily available source for off-the-shelf, patient-specific stem cells

It's in the bank: Human cord blood reprogrammed into embryonic-like stem cells

Biology / Biotechnology

created Oct 01, 2009 | popularity not rated yet | comments 0

Human umbilical cord blood cells may be far more versatile than previous research has indicated. Two independent studies, published by Cell Press in the October 2nd issue of the journal Cell Stem Cell, report ...


Molecular alliance that sustains embryonic stem cell state

Biology /

created Mar 04, 2008 | popularity 5 / 5 (1) | comments 0

One of the four ingredients in the genetic recipe that scientists in Japan and the U.S. followed last year to persuade human skin cells to revert to an embryonic stem cell state, is dispensable in ES cells, thanks to the ...


Cancer stem cells generated by cancer outgrowth

Medicine & Health / Cancer

created Apr 02, 2009 | popularity 5 / 5 (2) | comments 0

Scientists have discovered that growing mouse skin cells in spheres can lead to generation of cells with properties of cancer stem cells, even without genetic manipulation of stem cell genes. This unexpected finding, published ...


Recipe for cell reprogramming adds protein

Biology /

created Aug 06, 2008 | popularity 5 / 5 (2) | comments 0

A drug-like molecule called Wnt can be substituted for the cancer gene c-Myc, one of four genes added to adult cells to reprogram them to an embryonic-stem-cell-like state, according to Whitehead researchers. Researchers ...


Stanford scientists turn adult skin cells into muscle and vice versa

Biology / Cell & Microbiology

created Apr 30, 2009 | popularity 5 / 5 (3) | comments 1

In a study featured on the cover of the May issue of The FASEB Journal, researchers describe how they are able to reprogram human adult skin cells into other cell types in order to decipher the elusive mechanisms underlying reprog ...


Scientists identify embryonic stem cells by appearance alone

Biology /

created Aug 27, 2007 | popularity 4.7 / 5 (3) | comments 0

Some scientific results are hard to spot, especially in genetic research. Often scientists are unable to physically see if the gene they inserted into a cell has produced the desired trait. To overcome this problem researchers ...