Vaccine to cope with viral diversity in HIV

Medicine & Health / HIV & AIDS

Apr 27, 2007 | 4.5 / 5 (6) | 0

The ability of HIV-1 to develop high levels of genetic diversity and acquire mutations to escape immune pressures contributes to our difficulties in producing a vaccine. David Nickle et al present here an efficient algorithm ...

Novel mathematical model predicts new wave of drug-resistant HIV infections in San Francisco

Other Sciences / Mathematics

Feb 17, 2008 | 4.2 / 5 (9) | 1

A mathematical model shows that a new wave of drug-resistant HIV is rising among among men in San Francisco who have sex with men and that this trend will continue over the next few years, according to a new study from the ...

Prolonged nevirapine in breast-fed babies prevents HIV infection but leads to drug-resistant HIV

Medicine & Health / HIV & AIDS

Jan 05, 2009 | not rated yet | 0

Babies born to HIV-positive mothers and given the antiretroviral drug nevirapine through the first six weeks of life to prevent infection via breast-feeding are at high risk for developing drug-resistant HIV if they get infected ...

Challenges of HIV-1 subtype diversity

Medicine & Health / HIV & AIDS

May 21, 2008 | 5 / 5 (2) | 0

A review article in the New England Journal of Medicine explores the genetic variation of HIV-1 and its implications for preventing and treating the disease. Francine McCutchan, Ph.D., a researcher with the U.S. Military HIV Re ...

Viral recombination another way HIV fools the immune system

Medicine & Health / HIV & AIDS

Jul 21, 2008 | 5 / 5 (1) | 0

When individuals infected with HIV become infected with a second strain of the virus, the two viral strains can exchange genetic information, creating a third, recombinant strain of the virus. It is known that the presence ...

HIV isolate from Kenya provides clues for vaccine design

Medicine & Health / HIV & AIDS

Jan 02, 2008 | 4 / 5 (3) | 0

Two simple changes in its outer envelope protein could render the AIDS virus vulnerable to attack by the immune system, according to research from Kenya and the Fred Hutchinson Cancer Research Center published in PLoS Medicine.

New technology opens gateway to studying HIV-specific neutralizing antibodies

Medicine & Health / HIV & AIDS

Mar 16, 2009 | not rated yet | 0

Many scientists believe a vaccine that prevents HIV infection will need to stimulate the body to make neutralizing antibodies, infection-fighting proteins that prevent HIV from entering immune cells. Previous research has ...

MicroRNAs help control HIV life cycle

Chemistry / Biochemistry

Jun 25, 2009 | 4 / 5 (1) | 0

Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells. In particular, ...

New strategy proposed for designing antibody-based HIV vaccine

Medicine & Health / HIV & AIDS

Jun 14, 2009 | not rated yet | 0

WHAT: Most vaccines that protect against viruses generate infection-fighting proteins called antibodies that either block infection or help eliminate the virus before it can cause disease. Attempts to create a vaccine that ...

Researcher refining synthetic molecules to prevent HIV resistance

Medicine & Health / HIV & AIDS

Dec 16, 2008 | 5 / 5 (2) | 0

Evolving HIV viral strains and the adverse side effects associated with long-term exposure to current treatments propel scientists to continue exploring alternative HIV treatments. In a new study, a University of Missouri ...

New study finds HIV drug can persist in mothers' milk, increasing risk to them and their babies

Medicine & Health / HIV & AIDS

Aug 05, 2008 | not rated yet | 0

A drug commonly used in the developing world to prevent transmission of HIV from mother to child persists in the breast milk and blood of the mothers, putting them and their babies at risk for developing drug-resistant strains ...

Researchers discover gene that blocks HIV

Medicine & Health / HIV & AIDS

Feb 29, 2008 | 4.6 / 5 (196) | 3

A team of researchers at the University of Alberta has discovered a gene that is able to block HIV, and in turn prevent the onset of AIDS.

Ultra deep sequencing identifies HIV drug resistance at early stage

Medicine & Health / HIV & AIDS

Jun 16, 2007 | 4.1 / 5 (7) | 0

Rare, previously undetectable drug-resistant forms of HIV have been identified by Yale School of Medicine researcher Michael Kozal, M.D., using an innovative genome sequencing technology that quickly detects rare viral mutations.

A natural approach for HIV vaccine

Medicine & Health / HIV & AIDS

Mar 15, 2009 | 4 / 5 (1) | 0

(PhysOrg.com) -- For 25 years, researchers have tried and failed to develop an HIV vaccine, primarily by focusing on a small number of engineered "super antibodies" to fend off the virus before it takes hold. So far, these ...

New insight into selective binding properties of infectious HIV

Medicine & Health / HIV & AIDS

Dec 15, 2009 | not rated yet | 0

Free infectious HIV-1 is widely thought to be the major form of the virus in the blood of infected persons. U.S. Military HIV Research Program (MHRP) researchers, however, have demonstrated that essentially all of the infectious ...