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Search results for nuclear receptor
Determining the structure of nuclear receptor has implications for a host of diseases
Biology /
Sep 16, 2008 |
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In a study published this week in PLoS Biology, Eric Xu and colleagues have determined the molecular structure of a nuclear receptor, which regulates the expression of specific genes within cells, that may serve as a drug ...
DC-SCRIPT found to have prognostic value in breast cancer
Dec 14, 2009 |
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DC-SCRIPT, or dendritic cell-specific transcript, is a key regulator of nuclear receptor activity that may have prognostic value in breast cancer, according to a new study published online December 14 in the Journal of th ...
Nuclear hormone receptors, microRNAs form developmental switch
Apr 02, 2009 |
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A particular nuclear hormone receptor called DAF-12 and molecules called microRNAs in the let-7 family form a molecular switch that encourages cells in the larvae of a model worm to shift to a more developed state, said a ...
Growth hormone could promote cancer, according to new research
Sep 21, 2007 |
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Growth hormone and associated proteins could be responsible for promoting many types of cancer, including breast and prostate cancer, according to an Australian researcher.
Latest epidemic? High cholesterol, obesity in fruit flies
Dec 02, 2009 |
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How do fruit flies get high cholesterol and become obese? The same way as people do - by eating a diet that's too rich in fats.
Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals
Apr 23, 2009 |
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Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of the Opioid Growth Factor (OGF, [Met5]-enkephalin), a clinically important antitumor agent, is ...
RXR activation -- hope for new Parkinson's disease treatment
Medicine & Health / Neuroscience
Dec 11, 2009 |
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Following up on their previous work showing the rescue of dopamine neurons by chemicals that interact with the retinoid X receptor (RXR), researchers have now investigated the potential of these chemicals, known as RXR ligands, ...
Molecular imaging holds promise for early intervention in common uterine cancer
Oct 01, 2009 |
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A promising new molecular imaging technique may provide physicians and patients with a noninvasive way to learn more information about a type of cancer of the uterus lining called "endometrial carcinoma" -- one of the most ...
Dartmouth researchers show effects of low dose arsenic on development
Nov 14, 2007 |
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A team of Dartmouth Medical School (DMS) researchers has determined that low doses of arsenic disrupt the activity of a hormone critical in development. The finding is further evidence that arsenic at low doses (at levels ...
Plants on Steroids: Key Missing Link Discovered
Sep 08, 2009 |
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(PhysOrg.com) -- Researchers at the Carnegie Institution's Department of Plant Biology have discovered a key missing link in the so-called signaling pathway for plant steroid hormones (brassinosteroids). Many important signaling ...
Researchers create smaller and more efficient nuclear battery
Oct 07, 2009 |
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(PhysOrg.com) -- Batteries can power anything from small sensors to large systems. While scientists are finding ways to make them smaller but even more powerful, problems can arise when these batteries are ...
Doubts raised on nuclear industry viability
Nov 19, 2009 |
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(PhysOrg.com) -- The investment in nuclear power has been growing around the world over the last few years, being viewed as a means for countries to control their energy security, avoid the price fluctuations ...
Estrogen and progesterone receptor isoforms expression in the stomach of Mongolian gerbils
Oct 31, 2008 |
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Gerbils were treated with estradiol and E2+ progesterone. Stomach proteins were immunoblotted for Estrogen-alpha, ER-beta, progesterone receptor-A, PR-B. ER-alpha, PR-A and PR-B were detected. PR isoforms were not regulated ...
Improved estrogen reception may sharpen fuzzy memory
Jul 29, 2008 |
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Estrogen treatments may sharpen mental performance in women with certain medical conditions, but University of Florida researchers suggest that recharging a naturally occurring estrogen receptor in the brain may also clear ...
Common molecule notifies immune system of prostate cancer
Jan 10, 2008 |
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In experiments with mice, researchers have found that the body’s immune system can use a surprisingly common molecule to recognize prostate tumors. The molecule comes from a protein found in all cells of the body; however, ...
