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Plant polymerases IV and V are special forms of Polymerase II

Plant polymerases IV and V are special forms of Polymerase II

Biology /

created Jan 06, 2009 | popularity 5 / 5 (3) | comments 0

(PhysOrg.com) -- It's a little like finding out that Superman is actually Clark Kent. A team of biologists at Washington University in St. Louis has discovered that two vital cellular components, nuclear RNA ...


New gene-silencing pathway found in plants

Shedding light on the 'dark matter' of genetics: New gene-silencing pathway found in plants

Biology /

created Nov 17, 2008 | popularity 4.5 / 5 (2) | comments 0

(PhysOrg.com) -- Biologists at Washington University in St. Louis have made major headway in explaining a mechanism by which plant cells silence potentially harmful genes.


Molecule stops DNA replication in its tracks

Molecule stops DNA replication in its tracks

Biology /

created Oct 20, 2008 | popularity 4 / 5 (3) | comments 0

(PhysOrg.com) -- When a dividing cell duplicates its genetic material, a molecular machine called a sliding clamp travels along the DNA double helix, tethering the proteins that perform the replication. Researchers ...


Clearing jams in copy machinery

Other Sciences /

created Sep 19, 2005 | popularity not rated yet | comments 0

Bacteria and humans use a number of tools to direct perhaps the most important function in cells -- the accurate copying of DNA during cell division. New research published this week in Molecular Cell from the laboratory ...


Lab identifies new role for factor critical to transcription

Biology /

created Jun 17, 2008 | popularity 4.5 / 5 (2) | comments 0

The Stowers Institute's Shilatifard Lab has identified a new role for the elongation factor ELL in gene transcription by RNA polymerase II (Pol II) — the enzyme that synthesizes messenger RNA to carry genetic information ...


'Sloppier copier' surprisingly efficient

Biology / Cell & Microbiology

created Jul 15, 2009 | popularity 4.3 / 5 (4) | comments 3

The "sloppier copier" discovered by USC biologists is also the best sixth man in the DNA repair game, an article in the journal Nature shows.


Discovery of enzyme structure points way to creating less toxic anti-HIV drugs

Biology / Cell & Microbiology

created Oct 15, 2009 | popularity not rated yet | comments 0

By discovering the atomic structure of a key human enzyme, researchers at The University of Texas at Austin have pointed the way toward designing anti-HIV drugs with far less toxic side effects.


A Real Dracula Story

Biology / Cell & Microbiology

created Aug 27, 2009 | popularity 4.8 / 5 (4) | comments 0

Research, discovery and publishing in a prestigious journal are not as easy as 1-2-3. However, an outstanding mentor and a well-equipped lab made this feat possible for doctoral student Fei Jiang.


Coming together: tDNAs, RNA pol III and chromatid cohesion

Medicine & Health / Genetics

created Sep 02, 2007 | popularity 3.7 / 5 (3) | comments 0

In the September 1st issue of G&D, Drs. Rudra Dubey and Marc Gartenberg (UMDNJ) reveal a surprising new role for tDNAs and RNA polymerase III-associated proteins in sister chromatid cohesion.


How cell's master transcribing machine achieves near perfection

Biology /

created Jun 05, 2008 | popularity 3.7 / 5 (3) | comments 0

One of the most critical processes in biology is the transcription of genetic information from DNA to messenger RNA (mRNA), which provides the blueprint for the proteins that form the machinery of life. Now, researchers have ...


Gene transcribing machine takes halting, backsliding trip along the DNA

Gene transcribing machine takes halting, backsliding trip along the DNA

Chemistry / Biochemistry

created Jul 30, 2009 | popularity 5 / 5 (4) | comments 1

(PhysOrg.com) -- The body's nanomachines that read our genes don't run as smoothly as previously thought, according to a new study by University of California, Berkeley, scientists.


Research sheds light on the mechanics of gene transcription

Research sheds light on the mechanics of gene transcription

Biology /

created Jan 08, 2008 | popularity 4 / 5 (5) | comments 0

The molecular machinery behind gene transcription -- the intricate transfer of information from a segment of DNA to a corresponding strand of messenger RNA -- isn't stationed in special "transcription factories" ...


Tumor-killing virus selectively targets diseased brain cells

Medicine & Health / Research

created Feb 19, 2008 | popularity 4.6 / 5 (5) | comments 0

New findings show that a specialized virus with the ability to reproduce its tumor-killing genes can selectively target tumors in the brains of mice and eliminate them. Healthy brain tissue remained virtually untouched, according ...


Some French women, too thin, don't see it that way: study

Medicine & Health / Health

created Apr 23, 2009 | popularity 4 / 5 (2) | comments 1

France has by far the highest proportion of clinically underweight women in Europe, but only half of them think they are too thin, according to a new study.


Biologists find optimistic worms are ready for rapid recovery

Biology / Cell & Microbiology

created Mar 09, 2009 | popularity not rated yet | comments 0

For the tiny soil-dwelling nematode worm Caenorhabditis elegans, life is usually a situation of feast or famine. Researchers at the California Institute of Technology (Caltech) have found that this worm has evolved a surprisingly ...