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Tracking the molecular pathway to mixed-lineage leukemia
Dec 15, 2008 |
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Infants and adults with the blood cancer mixed-lineage leukemia (MLL) typically have a poor prognosis, and most infants die before their first birthdays. Although there are varying causes of MLL, most cases are caused by ...
Novel role of protein in generating amyloid-beta peptide
Apr 27, 2009 |
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A defining hallmark of Alzheimer's disease is the accumulation of the amyloid β protein (Aβ), otherwise known as "senile plaques," in the brain's cortex and hippocampus, where memory consolidation occurs. Researchers ...
Nature-inspired technology creates engineered antibodies to fight specific diseases
Mar 25, 2009 |
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(PhysOrg.com) -- When viruses and bacteria invade the body, the immune system generates protective proteins called antibodies that bind to and destroy the invading pathogens.
Drought resistance explained
Nov 09, 2009 |
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Much as adrenaline coursing through our veins drives our body's reactions to stress, the plant hormone abscisic acid (ABA) is behind plants' responses to stressful situations such as drought, but how it does ...
Protein found that regulates gene critical to dopamine-releasing brain cells
Sep 10, 2008 |
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Researchers have identified a protein they say appears to be a primary player in maintaining normal functioning of an important class of neurons – those brain cells that produce, excrete and then reabsorb dopamine neurotransmitters. ...
Protein helps immune cells to divide and conquer
Mar 08, 2009 |
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Researchers at the University of California, San Diego School of Medicine have identified a key protein that is required for immune cells called B lymphocytes to divide and replicate themselves. The rapid generation of large ...
Protein linked to Alzheimer's disease doesn't act alone
Jun 10, 2009 |
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A team of U.S. investigators led by neuroscientists at Georgetown University Medical Center (GUMC) are steadily uncovering the role that amyloid precursor protein (APP) - the protein implicated in development of Alzheimer's ...
Scientists demonstrate role of protein in distinguishing chromosome ends from DNA breaks
Sep 17, 2009 |
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The Stowers Institute's Baumann Lab has demonstrated how human cells protect chromosome ends from misguided repairs that can lead to cancer. The work, published in The EMBO Journal, a publication of the European Molecular Biolog ...
Researchers Find Shared Motif in Membrane Transport Proteins Found in Plants, Bacteria
Jun 02, 2009 |
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(PhysOrg.com) -- University of Arkansas researchers have characterized a membrane receptor protein and its binding mechanism from chloroplasts in plants and determined that it shares a commonly shaped binding ...
Photonic crystal biosensors detect protein-DNA interactions
Biology /
Sep 23, 2008 |
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Scientists at the University of Illinois have developed a new class of disposable, microplate-based optical biosensors capable of detecting protein-DNA interactions. Based on the properties of photonic crystals, the biosensors ...
Researchers identify novel regulatory mechanism in inflammatory signaling of immune cells
Jan 08, 2009 |
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(PhysOrg.com) -- Using cancer cells that were originally isolated from an anaplastic large cell lymphoma patient, two researchers, including a faculty member of The University of Texas at Austin's College of Pharmacy, have ...
Long-term memory controls discovered
Jan 13, 2006 |
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Harvard biologists say research on the long-term memory in fruit flies may lead to new therapeutics to treat human memory loss.
Worth a thousand words: Hopkins researchers paint picture of cancer-promoting culprit
Jan 04, 2008 |
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They say that a picture can be worth a thousand words. This especially is true for describing the structures of molecules that function to promote cancer. Researchers at Johns Hopkins have built a three-dimensional picture ...
Scientists discover novel histone demethylase protein complex
Biology /
Dec 05, 2008 |
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The Stowers Institute's Workman Lab has discovered a novel histone demethylase protein complex characterized in work published today in Molecular Cell.
Mutant host cell protein sequesters critical HIV-1 element
Medicine & Health / HIV & AIDS
Jan 15, 2009 |
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Scientists have identified a new way to inhibit a molecule that is critical for HIV pathogenesis. The research, published by Cell Press in the January 16th issue of the journal Molecular Cell, presents a target for develo ...
