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Freeing protein-based drugs from bacteria's natural traps

Chemistry /

created Oct 13, 2008 | popularity not rated yet | comments 0

In a finding that could speed the development of new protein-based drugs for fighting diabetes, hepatitis, and other diseases, researchers are reporting progress toward preventing or destroying an unusual structure that reduces ...


Research team maps cell interactions

Chemistry /

created Oct 29, 2008 | popularity 4.5 / 5 (2) | comments 0

(PhysOrg.com) -- Proteins make up the machinery of the cell. Their interaction with each other is responsible for how the cell functions within a living organism. Intrigued by what these interactions may look like, scientists ...


Researchers discover 'on switch' for cell death signaling mechanism

Biology /

created Jan 05, 2009 | popularity 4.5 / 5 (6) | comments 0

Scientists at Burnham Institute for Medical Research (Burnham) have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for ...


Of Mutants and Mechanisms: Researching Growth-Regulation Proteins That Underlie Cancer

Of Mutants and Mechanisms: Researching Growth-Regulation Proteins That Underlie Cancer

Medicine & Health / Cancer

created Nov 09, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) --A University of Arkansas researcher will study potential cancer-causing mutants of a protein involved in cell growth regulation, thanks to a supplemental grant from the National Institutes ...


Powerhouses in the cell dismantled

Biology / Cell & Microbiology

created Oct 15, 2009 | popularity not rated yet | comments 0

All of life is founded on the interactions of millions of proteins. These are the building blocks for cells and form the molecular mechanisms of life. The problem is that proteins are extremely difficult to study, particularly ...


Researchers shed light on how proteins find their shapes

Researchers shed light on how proteins find their shapes

Chemistry / Biochemistry

created Feb 23, 2009 | popularity 4 / 5 (1) | comments 0

(PhysOrg.com) -- Researchers from the California Institute of Technology (Caltech) and the University of California at San Diego (UCSD) have brought together UCSD theoretical modeling and Caltech experimental ...


Research team identifies key molecules that inhibit viral production

Medicine & Health / Research

created Mar 10, 2009 | popularity not rated yet | comments 0

The research, led by Professor Donny Strosberg of Scripps Florida, was published on March 4, 2009, in the Journal of General Virology's advance, online edition, Papers in Press.


Reaching the summit of protein dynamics

Reaching the summit of protein dynamics

Biology / Cell & Microbiology

created Dec 10, 2009 | popularity 5 / 5 (1) | comments 0

Understanding the incredibly speedy atomic mechanisms at work when a protein transitions from one shape to another has been an elusive scientific goal for years, but an essential one for elucidating the full ...


Aging: Worms, Flies & Yeast Are More Like Us than Previously Expected

Biology / Cell & Microbiology

created Mar 13, 2009 | popularity 5 / 5 (4) | comments 1

When it comes to the aging process, yeast, nematode worms and fruit flies have more in common with humans than previously expected. In addition to highlighting the similarities between species, a large-scale human protein ...


Researchers discover structure of key Ebola protein

Biology /

created Jan 12, 2009 | popularity 5 / 5 (4) | comments 1

Research led by Iowa State University scientists has them a step closer to finding a way to counter the Ebola virus.


Engineered protein-like molecule protects cells against HIV infection

Medicine & Health / HIV & AIDS

created Aug 17, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- With the help of the human immunodeficiency virus (HIV) and molecular engineering, researchers have designed synthetic protein-like mimics convincing enough to interrupt unwanted biological conversations ...


Building a better protein

Chemistry / Biochemistry

created Feb 23, 2009 | popularity 4.5 / 5 (2) | comments 0

Proteins are widely viewed as a promising alternative to synthetic chemicals in everything from medications to hand lotion. The naturally occurring molecules have been shown to be more efficient and effective than many of ...


Researchers describe molecular 'two-step' leading to protein clumps of Huntington's disease

Biology / Cell & Microbiology

created Mar 08, 2009 | popularity not rated yet | comments 0

In a paper published in the early online version of Nature Structural and Molecular Biology, researchers at the University of Pittsburgh School of Medicine deconstruct the first steps in an intricate molecular dance that m ...


‘Designer molecules’ being developed to fight disease

Medicine & Health / Other

created Jun 12, 2009 | popularity 3 / 5 (1) | comments 0

(PhysOrg.com) -- Researchers in the Department of Cardiovascular Sciences at the University of Leicester are developing a new way to make protein based drugs with potential applications in stroke, vascular inflammation, blood ...


Scientists obtain clearer view of how eye lens proteins are sorted

Biology / Cell & Microbiology

created Nov 03, 2009 | popularity not rated yet | comments 0

New research reveals how proteins that are critical for the transparency of the eye lens are properly sorted and localized in membrane bilayers. The study, published by Cell Press in the November 3rd issue of Biophysical Jo ...