Search results for signaling protein:
Unraveling how cells respond to low oxygen
Aug 05, 2009 |
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Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. The REDD1 protein is a critical inhibitor of the mTOR signaling pathway, ...
Protein helps immune cells to divide and conquer
Mar 08, 2009 |
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Researchers at the University of California, San Diego School of Medicine have identified a key protein that is required for immune cells called B lymphocytes to divide and replicate themselves. The rapid generation of large ...
Protein that promotes cancer cell growth identified
Jul 24, 2009 |
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Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer ...
New method for detection of phosphoproteins reveals regulator of melanoma invasion
Apr 09, 2009 |
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Scientists have developed a new approach for surveying phosphorylation, a process that is regulated by critical cell signaling pathways and regulates several key cellular signaling events. The research, published by Cell ...
What makes stem cells tick?
Aug 06, 2009 |
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Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...
Of Mutants and Mechanisms: Researching Growth-Regulation Proteins That Underlie Cancer
Nov 09, 2009 |
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(PhysOrg.com) --A University of Arkansas researcher will study potential cancer-causing mutants of a protein involved in cell growth regulation, thanks to a supplemental grant from the National Institutes ...
New insight into an old reaction: Adenylylation regulates cell signaling
Apr 09, 2009 |
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A new study reveals the importance of adenylylation in the regulation of cell signaling from bacteria to higher organisms. The research, published by Cell Press in the April 10th issue of the journal Molecular Cell, provid ...
Why the thumb of the right hand is on the left hand side
May 22, 2009 |
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It is the concentration of a few signaling molecules that determines the fate of individual cells during the early development of organisms. In the renowned journal Current Biology, a team of molecular biologists led by Pia ...
Blocking signal molecule can prevent growth of large intestine and colon cancer
Sep 23, 2009 |
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By seeing what substances and molecules affect the development of our diseases, we can develop drugs that prevent or cure diseases. In her dissertation at Kalmar University in Sweden, Ann Novotny has found that the signal ...
Protein is key to embryonic stem cell differentiation
Mar 18, 2009 |
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Investigators at Burnham Institute for Medical Research (Burnham) have learned that a protein called Shp2 plays a critical role in the pathways that control decisions for differentiation or self-renewal in both human embryonic ...
'Disordered' amino acids may really be there to provide wiggle room for signaling protein
May 26, 2009 |
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Sections of proteins previously thought to be disordered may in fact have an unexpected biological role - providing certain proteins room to move -- according to a study published by researchers at Fox Chase Cancer Center ...
Taking the conversation inside: Enhancing signals in cell interior
Mar 19, 2009 |
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Scientists used to think most of the exchange of information between cells was conducted at the surface, where cell receptors receive signals from other cells.
Crosstalk between critical cell-signaling pathways holds clues to tumor invasion and metastasis
Nov 25, 2009 |
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Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers ...
Researchers have immune cells running in circles
Nov 02, 2009 |
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(PhysOrg.com) -- University of Illinois at Chicago College of Medicine researchers have identified the important role a protein plays in the body's first line of defense in directing immune cells called neutrophils toward ...
Fate in fly sensory organ precursor cells could explain human immune disorder
Jun 21, 2009 |
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(June 21, 2009) - Notch signaling helps determine the fate of a number of different cell types in a variety of organisms, including humans. In an article that appears in the current issue of Nature Cell Biology, researchers at Bay ...
