Search results for sonic hedgehog
New insight into most common forebrain malformation
Aug 11, 2008 |
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St. Jude Children's Research Hospital scientists have identified one of the molecular mechanisms underlying the genetic brain malformation called holoprosencephaly (HPE). The findings not only yield insights into the most ...
Sega Puts The Sonic Into Panasonic Mobile Phones
May 20, 2005 |
2.7 / 5 (10) |
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Panasonic today announced that it has secured the rights to feature SEGA’s blockbuster game, Sonic The Hedgehog, on its new series of mobile phones. As previewed on SEGA’s booth at the E3 premier game show ...
Sonic Hedgehog variations linked to recurrence, survival and response to therapy of bladder cancer
Dec 09, 2009 |
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Genetic variations in the Sonic Hedgehog pathway increase the likelihood of recurrence, reduce survival time and limit response to therapy for people with non-muscle invasive bladder cancer, scientists from The University ...
Researchers Discover Tiny Cellular Antennae Trigger Neural Stem Cells
Biology /
Aug 12, 2008 |
4.8 / 5 (18) |
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(PhysOrg.com) -- Yale University scientists today reported evidence suggesting that the tiny cilia found on brain cells of mammals, thought to be vestiges of a primeval past, actually play a critical role ...
Researchers find new molecule to block ‘Hedgehog’ signaling in cancer, development
Biology /
Jan 19, 2009 |
5 / 5 (2) |
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(PhysOrg.com) -- Researchers have achieved a feat drug developers had thought difficult, if not impossible, discovering a compound that blocks the functioning of a key developmental protein by binding to an “undruggable” ...
Human ES cells progress slowly in myelin's direction
Apr 09, 2009 |
4.5 / 5 (4) |
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Scientists from the University of Wisconsin, USA, report in the journal Development the successful generation from human embryonic stem cells of a type of cell that can make myelin, a finding that opens up new possibilities for bo ...
Researchers find key to Sonic hedgehog control of brain development
Oct 28, 2008 |
4.4 / 5 (7) |
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University of Pennsylvania School of Medicine researchers have discovered how the expression of the Sonic hedgehog gene is regulated during brain development and how mutations that alter this process cause ...
Mechanism in cells that generate malignant brain tumors may offer target for gene therapy
Oct 24, 2008 |
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Researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute who first isolated cancer stem cells in adult brain tumors in 2004 have now identified a molecular mechanism that is involved in the development ...
Glypican-3 gene function in regulating body size helps inform novel cancer treatments
May 12, 2008 |
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In a leading study that has implications for the development of novel therapies for a number of breast, lung and ovarian cancers that have lost the expression of a gene called glypican-3 (GPC3), Sunnybrook researchers have ...
Researchers identify gene that spurs deadly brain cancer
Dec 03, 2009 |
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Howard Hughes Medical Institute (HHMI) researchers have identified a new factor that is necessary for the development of many forms of medulloblastoma, the most common type of malignant childhood brain cancer.
New Clues to Limb Formation (and Loss) in Some Sea Mammals
Biology /
May 23, 2006 |
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Researchers from the Northeastern Ohio Universities College of Medicine have revealed the genetic basis behind one of the best-documented examples of evolutionary change in the fossil record: how whales lost ...
Raytheon, Cessna Receive NASA Sonic Boom Research Grants
Jul 12, 2005 |
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Two Wichita-based general aviation manufacturers are participating in research projects studying how to lessen the window-rattling sonic booms created by supersonic flight.
Replacing the cells lost in Parkinson disease
Dec 03, 2007 |
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Parkinson disease (PD) is caused by the progressive degeneration of brain cells known as dopamine (DA) cells. Replacing these cells is considered a promising therapeutic strategy. Although DA cell–replacement therapy by transplantation ...
Fetal alcohol study uncovers new facts
Jan 23, 2007 |
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U.S. medical researchers have found cholesterol supplementation prevents fetal alcohol spectrum defects in alcohol-exposed zebra fish embryos.
Some skin cancer may be mediated by primary cilia activity
Aug 23, 2009 |
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Tiny, solitary spikes that stick out of nearly every cell in the body play a central role in a type of skin cancer, new research has found. The discovery in mice shows that the microscopic structures known as primary cilia ...
