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Getting on 'the GABA receptor shuttle' to treat anxiety disorders

Medicine & Health / Psychology & Psychiatry

created Oct 22, 2009 | popularity 4.5 / 5 (2) | comments 1

There are increasingly precise molecular insights into ways that stress exposure leads to fear and through which fear extinction resolves these fear states. Extinction is generally regarded as new inhibitory learning, but ...


How protein receptors on cells switch on and off

How protein receptors on cells switch on and off

Biology /

created Jan 16, 2009 | popularity 5 / 5 (3) | comments 0

Cornell researchers have provided new insight into the molecular mechanism underlying an essential cellular system. They have discovered how receptors on cell surfaces turn off signals from the cell's environment, ...


Better understanding of blood vessel constrictor needed to harness its power for patients

Better understanding of blood vessel constrictor needed to harness its power for patients

Medicine & Health / Research

created Sep 18, 2008 | popularity not rated yet | comments 0

To harness endothelin-1's power to constrict blood vessels and help patients manage high blood pressure or heart failure, scientists must learn more about how endothelin functions naturally and in disease ...


Scientists Discover An Ancient Odor-Detecting Mechanism in Insects

Scientists Discover An Ancient Odor-Detecting Mechanism in Insects

Biology /

created Jan 08, 2009 | popularity 3.7 / 5 (3) | comments 1

(PhysOrg.com) -- In 1913 Theodore Roosevelt added cartographer to his resume when he and his crew ventured up an unspeakably dangerous and uncharted tributary named the River of Doubt. Now, on a charting expedition ...


Designing probiotics that ambush gut pathogens

Biology / Cell & Microbiology

created Sep 08, 2009 | popularity not rated yet | comments 0

Researchers in Australia are developing diversionary tactics to fool disease-causing bacteria in the gut. Many bacteria, including those responsible for major gut infections, such as cholera, produce toxins that damage human ...


Pandemic flu can infect cells deep in the lungs, says new research

Pandemic flu can infect cells deep in the lungs, says new research

Biology / Biotechnology

created Sep 10, 2009 | popularity 3.7 / 5 (3) | comments 1

(PhysOrg.com) -- Pandemic swine flu can infect cells deeper in the lungs than seasonal flu can, according to a new study published today in Nature Biotechnology. The researchers, from Imperial College London ...


Researchers create first model for retina receptors

Chemistry /

created Sep 30, 2008 | popularity 4.4 / 5 (7) | comments 0

A team of scientists at the University of Oklahoma Health Sciences Center has created the first genetic research model for a microscopic part of the eye that when missing causes blindness. The research appears in a recent ...


Cell surface receptors are all 'talk' in T cell stimulation

Medicine & Health / Research

created Jun 12, 2008 | popularity 5 / 5 (1) | comments 0

Understanding the mechanisms that drive healthy immune responses is important when it comes to combating autoimmune diseases, which occur when cells that should attack invading organisms turn on the body instead.


Natural born killers -- how the body's frontline immune cells decide which cells to destroy

Natural born killers -- how the body's frontline immune cells decide which cells to destroy

Medicine & Health / Research

created Jul 28, 2009 | popularity 4.5 / 5 (4) | comments 0

(PhysOrg.com) -- The mechanism used by 'Natural Killer' immune cells in the human body to distinguish between diseased cells, which they are meant to destroy, and normal cells, which they are meant to leave ...


Red alert! How disease disables tomato plant's 'intruder alarm'

Biology /

created Dec 04, 2008 | popularity 5 / 5 (4) | comments 0

How a bacterium overcomes a tomato plant's defences and causes disease, by sneakily disabling the plant's intruder detection systems, is revealed in new research out today (4 December) in Current Biology.


This is your brain on fatty acids

Medicine & Health / Neuroscience

created Oct 30, 2009 | popularity 4.8 / 5 (6) | comments 1

Saturated fats have a deservedly bad reputation, but Johns Hopkins scientists have discovered that a sticky lipid occurring naturally at high levels in the brain may help us memorize grandma's recipe for cinnamon buns, as ...


A molecule keeps anxiety down

A molecule keeps anxiety down

Medicine & Health / Research

created Aug 19, 2008 | popularity 4.7 / 5 (9) | comments 0

(PhysOrg.com) -- The link between emotions and experiences determines many aspects of our daily life. It allows us to recognize pretty objects or harmful situations. These links are created when nerve cells ...


Morphine dependency blocked by single genetic change

Medicine & Health / Research

created Jan 28, 2008 | popularity 4 / 5 (3) | comments 0

Morphine’s serious side effect as a pain killer – its potential to create dependency – has been almost completely eliminated in research with mice by genetically modifying a single trait on the surface of neurons. The study ...


1918 influenza virus

Researchers explain spread of 1918 flu pandemic

Biology /

created Feb 18, 2008 | popularity 4.7 / 5 (29) | comments 0

MIT researchers have explained why two mutations in the H1N1 avian flu virus were critical for viral transmission in humans during the 1918 pandemic outbreak that killed at least 50 million people.


EphA4 -- the molecular transformer

EphA4 -- the molecular transformer

Chemistry / Analytical Chemistry

created Oct 23, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- EphA4 is a protein which is attached to the surfaces of many types of human cells and plays a role in a wide range of biological processes. EphA4 functions by binding to ephrin ligands, cell ...