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Images of Neurons in Culture

Scientists make headway in understanding Alzheimer's disease

Medicine & Health / Research

created Feb 05, 2009 | popularity 4.6 / 5 (5) | comments 0

Scientists at UC Santa Barbara have discovered that a protein called BAG2 is important for understanding Alzheimer's disease and may open up new targets for drug discovery. They are ready to move from studying ...


Compounds have potential for diagnosis, treatment of Alzheimer's disease

Medicine & Health / Medications

created Aug 21, 2008 | popularity 4.4 / 5 (5) | comments 0

New research suggests that a select group of compounds that interact with a protein in the brain might be used in the early diagnosis and treatment of Alzheimer's disease and other dementia disorders.


Protein inhibitor helps rid brain of toxic tau protein

Protein inhibitor helps rid brain of toxic tau protein

Medicine & Health / Neuroscience

created Sep 29, 2009 | popularity 4.8 / 5 (5) | comments 0

Inhibiting the protein Hsp70 rapidly reduces brain levels of tau, a protein associated with Alzheimer's disease when it builds up abnormally inside nerve cells affecting memory, neuroscientists at the University ...


Mechanism of Alzheimer's suggests combination therapy needed

Medicine & Health / Diseases

created Mar 17, 2009 | popularity 5 / 5 (2) | comments 0

Researchers at the University of Illinois at Chicago College of Medicine have discovered a mode of action for mysterious but diagnostic protein snarls found in the brains of Alzheimer's patients that suggests a one-two punch ...


Researchers surprised by similar structures in Sanfilippo syndrome and Alzheimer's disease

Researchers surprised by similar structures in Sanfilippo syndrome and Alzheimer's disease

Medicine & Health / Neuroscience

created May 04, 2009 | popularity 5 / 5 (1) | comments 0

Researchers seeking to understand the causes of a rare genetic lysosomal storage disease, Sanfilippo syndrome type B, were surprised to find protein aggregates, known as neurofibrillary tangles, that are usually ...


Cancer-related protein may play key role in Alzheimer's disease

Medicine & Health / Research

created Feb 28, 2008 | popularity 4.8 / 5 (6) | comments 0

The cancer-related protein Akt may profoundly influence the fate of the tau protein, which forms bundles of tangled nerve cell fibers in the brain associated with Alzheimer’s disease, reports a new study led by researchers ...


Scientists identify 'missing link' in process leading to Alzheimer's disease

Medicine & Health / Diseases

created Feb 08, 2007 | popularity 4.9 / 5 (10) | comments 0

Scientists at the University of Virginia have identified what appears to be a major missing link in the process that destroys nerve cells in Alzheimer's disease, an incurable disease that slowly destroys memory and cognitive ...


Stress and Tau Phosphorylation

A possible mechanistic link between stress and the development of Alzheimer tangles

Medicine & Health / Research

created Jun 15, 2007 | popularity 4.7 / 5 (6) | comments 0

Subjecting mice to repeated emotional stress, the kind we experience in everyday life, may contribute to the accumulation of neurofibrillary tangles, one of the hallmarks of Alzheimer’s disease, report researchers ...


'Super' aged brains reveal first secrets of sharp memory in old age

Medicine & Health / Research

created Nov 16, 2008 | popularity 4.7 / 5 (37) | comments 0

Maybe you have an 85-year-old grandfather who still whips through the newspaper crossword puzzle every morning or a 94-year-old aunt who never forgets a name or a face. They don't seem to suffer the ravages of memory that ...


Alzheimer's discovery could bring early diagnosis, treatment closer

Chemistry / Biochemistry

created May 22, 2009 | popularity 5 / 5 (8) | comments 0

(PhysOrg.com) -- A discovery made by researchers at McGill University and the affiliated Lady Davis Research Institute for Medical Research at Montreal's Jewish General Hospital offers new hope for the early diagnosis and ...


Plaques And Tangles

Gene variation linked to earlier onset of Alzheimer's symptoms

Medicine & Health / Research

created Jun 09, 2008 | popularity 5 / 5 (3) | comments 0

Investigators at Washington University School of Medicine in St. Louis have identified a genetic variation associated with an earlier age of onset in Alzheimer's disease.


Pin1 is beneficial in Alzheimer's disease, detrimental to some forms of dementia

Medicine & Health / Research

created Apr 23, 2008 | popularity 4.3 / 5 (4) | comments 0

The most common form of dementia, Alzheimer’s disease, and a relatively rare hereditary form of dementia, frontotemporal dementia with parkinsonism-17, share a common pathology: Both are the result of an overaccumulation ...


Novel mouse gene reduces major pathologies associated with Alzheimer's disease

Medicine & Health / Neuroscience

created Nov 11, 2009 | popularity 3.8 / 5 (4) | comments 0

A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer's disease (AD). The research, published by Cell Press in the November 12 issue ...


PET Scan for Brain Aging

New assessment technique lets scientists see brain aging before symptoms appear

Medicine & Health / Research

created Jan 06, 2009 | popularity 4.7 / 5 (3) | comments 0

UCLA scientists have used innovative brain-scan technology developed at UCLA, along with patient-specific information on Alzheimer's disease risk, to help diagnose brain aging, often before symptoms appear. ...


Lithium chloride slows onset of skeletal muscle disorder

Medicine & Health / Research

created Mar 18, 2008 | popularity 4.4 / 5 (9) | comments 0

A new UC Irvine study finds that lithium chloride, a drug used to treat bipolar disorder, can slow the development of inclusion body myositis, a skeletal muscle disease that affects the elderly.