Search results for +"AKT" :
A potential sugar fix for tumorsResearchers at the Duke School of Medicine apparently have solved the riddle of why cancer cells like sugar so much, and it may be a mechanism that could lead to better cancer treatments. |
Calorie restriction limits and obesity fuels development of epithelial cancersA restricted-calorie diet inhibited the development of precancerous growths in a two-step model of skin cancer, reducing the activation of two signaling pathways known to contribute to cancer growth and development, researchers ... |
Cancer-related protein may play key role in Alzheimer's diseaseThe cancer-related protein Akt may profoundly influence the fate of the tau protein, which forms bundles of tangled nerve cell fibers in the brain associated with Alzheimer’s disease, reports a new study led by researchers ... |
Inverted DNA turns quiet developmental gene into a potent driver of t-cell lymphomaFeb 27, 2008 | pda version
A gene crucial for embryonic development can quickly become a potent cancer promoter in adult mice after a genetic misalignment, according to researchers from Fox Chase Cancer Center, causing white blood cells to become cancerous ... |
Oncoproteins double-team and destroy vital tumor-suppressorFeb 14, 2008 | pda version
Two previously unconnected cancer-promoting proteins team up to ambush a critical tumor suppressor by evicting it from the cell's nucleus and then marking it for death by a protein-shredding mechanism, a team led by scientists ... |
Anti-parasite drug may provide new way to attack HIVA drug already used to treat parasitic infections, and once looked at for cancer, also attacks the human immunodeficiency virus (HIV) in a new and powerful way, according to research published today online in the open access ... |
Mutant gene identified as villain in hardening of the arteriesA genetic mutation expands lesions in the aorta and promotes coronary atherosclerosis, more commonly known as hardening of the arteries, according to a study by Yale School of Medicine in Cell Metabolism. |
Mechanism for regulation of growth and differentiation of adult muscle stem cells is revealedDuring muscle regeneration, which is a natural response to injury and disease, environmental cues cause adult muscle stem cells (satellite cells) to shift from dormancy to actively building new muscle tissue. |
Human C-reactive protein regulates myeloma tumor cell growth and survivalScientists report that a protein best known as a common marker of inflammation plays a key role in the progression of human cancer. The research, published by Cell Press in the September issue of the journal Cancer Cell, ... |
M. D. Anderson team identifies new oncogene for brain cancerAn overexpressed gene found at the scene of a variety of tumors is implicated in the development of two types of malignant brain cancer in a paper by researchers at The University of Texas M. D. Anderson Cancer Center to ... |
MIT reports key pathway in synaptic plasticityScientists are keenly studying how neurons form synapses--the physical and chemical connections between neurons--and the "pruning" of neural circuits during development, not least because synaptic abnormalities may partially ... |
Scientists identify protein key to breast cancer spread, potential new drug targetResearchers at the Kimmel Cancer Center at Jefferson have identified a protein that they say is key to helping a quarter of all breast cancers spread. The finding, reported online the week of April 9, 2007 in the journal ... |
Researchers discover variants of natural tumor suppressorBuilding on their 2005 discovery of an enzyme that is a natural tumor suppressor, researchers at the University of California, San Diego School of Medicine have now identified two variants of that enzyme which could provide ... |
Molecular differences between early and advanced melanomas could provide new drug targetsThe cell-signaling molecule Akt is a primary trigger that leads malignant melanomas on the skin's surface to begin growing vertically beneath the skin and turn into deadly invasive cancers, scientists have found. Understanding ... |
'Bridge' protein spurs deadliest stages of breast cancerA protein known for its ability to "bridge" interactions between other cellular proteins may spur metastasis in breast cancer, the disease’s deadliest stage, a study from Burnham Institute for Medical Research has found. |
