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Scientists demonstrate role of protein in distinguishing chromosome ends from DNA breaks

Medicine & Health / Cancer

created Sep 17, 2009 | popularity not rated yet | comments 0

The Stowers Institute's Baumann Lab has demonstrated how human cells protect chromosome ends from misguided repairs that can lead to cancer. The work, published in The EMBO Journal, a publication of the European Molecular Biolog ...


Male sex chromosome losing genes by rapid evolution, study reveals

Male sex chromosome losing genes by rapid evolution, study reveals

Biology / Evolution

created Jul 17, 2009 | popularity 4.1 / 5 (15) | comments 11

Scientists have long suspected that the sex chromosome that only males carry is deteriorating and could disappear entirely within a few million years, but until now, no one has understood the evolutionary ...


Sex Talk Revelations of the Lonely Y Chromosome

Medicine & Health / Genetics

created Sep 09, 2009 | popularity 4.3 / 5 (3) | comments 3

(PhysOrg.com) -- In the week that the University of Leicester celebrates the 25th anniversary of the discovery of DNA fingerprinting (Thursday September 10) new findings from the world-renowned University of Leicester Department ...


'Achilles' heel' in Y chromosome linked to sex disorders

'Achilles' heel' in Y chromosome linked to sex disorders

Medicine & Health / Research

created Sep 03, 2009 | popularity not rated yet | comments 0

The unique mechanism behind the evolutionary survival of the human Y chromosome may also be responsible for a range of sex disorders, from failed sperm production to sex reversal to Turner Syndrome.


Researchers discover mechanism that prevents two species from reproducing

Biology / Biotechnology

created Oct 26, 2009 | popularity 5 / 5 (6) | comments 3

Cornell researchers have discovered a genetic mechanism in fruit flies that prevents two closely related species from reproducing, a finding that offers clues to how species evolve.


New study rewrites textbook on key genetic phenomenon

Medicine & Health / Genetics

created Jul 01, 2009 | popularity 4 / 5 (2) | comments 1

Because females carry two copies of the X chromosome to males' one X and one Y, they harbor a potentially toxic double dose of the over 1000 genes that reside on the X chromosome.


The story of X -- evolution of a sex chromosome

The story of X -- evolution of a sex chromosome

Biology / Cell & Microbiology

created Apr 16, 2009 | popularity 4.7 / 5 (11) | comments 1

(PhysOrg.com) -- Move over, Y chromosome - it's time X got some attention. In the first evolutionary study of the chromosome associated with being female, University of California, Berkeley, biologist Doris ...


Amount of gene surplus determines severity of mental retardation in males

Medicine & Health / Genetics

created Dec 10, 2009 | popularity 5 / 5 (1) | comments 0

Researchers have discovered a new explanation for differences in the severity of mental illness in males. The more excess copies of a certain gene, the more serious the handicap. The genetic defect is situated on the X-chromosome; ...


Dogs, humans, put heads together to find cure for brain cancer

Medicine & Health / Genetics

created Jul 06, 2009 | popularity not rated yet | comments 0

Pinpointing the genes involved in human brain cancer can be like looking for a needle in a haystack, and sometimes the needle you find may not be the right one. By comparing human and canine genomes, researchers at North ...


Novel genetic region identified for childhood asthma in Mexicans

Medicine & Health / Genetics

created Aug 28, 2009 | popularity 5 / 5 (1) | comments 0

Genetic variants in a region on chromosome 9q may influence asthma development in Mexican children, according to research published in the August 28 issue of the open-access journal PLoS Genetics.


New research shows key player in mitosis not required for chromosome alignment

New research shows key player in mitosis not required for chromosome alignment

Biology / Cell & Microbiology

created Jul 06, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- K-fibers, structures long thought to play a key role in the alignment of chromosomes prior to cell division, are not required after all, say Indiana University and New York State Department ...


Researchers determine the composition of centromeric chromatin

Biology / Cell & Microbiology

created Sep 28, 2009 | popularity not rated yet | comments 0

The Stowers Institute's Gerton Lab has provided new evidence to clarify the structure of nucleosomes containing Cse4, a centromere-specific histone protein required for proper kinetochore function, which plays a critical ...


Cloning plants from seeds

Biology / Biotechnology

created Dec 15, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Wageningen geneticists (The Netherlands) are developing a method to replicate the parents of a chosen plant. Known as 'reverse breeding', this will have a big impact for the breeding industry.


Female human embryos adjust the balance of X chromosomes before implantation

Medicine & Health / Research

created Jun 29, 2009 | popularity not rated yet | comments 0

Dutch researchers have found the first evidence that a process of inactivating the X chromosome during embryo development and implantation, which was known to occur in mice but unknown in humans, does, in fact, take place ...


Common weed could provide clues on aging and cancer

Chemistry / Biochemistry

created Oct 26, 2009 | popularity 4 / 5 (2) | comments 0

A common weed and human cancer cells could provide some very uncommon details about DNA structure and its relationship with telomeres and how they affect cellular aging and cancer, according to a team led by scientists from ...