A new strategy for treating a variety of diseases known as RNA-repeat expansion disorders, which affect millions of people, has shown promise in proof-of-principle tests conducted by scientists at Scripps Research.
Biochemistry
Nov 6, 2020
0
138
The first few days of embryonic development are a critical point for determining the failure or success of a pregnancy. Because relatively few cells make up the embryo during this period, the health of each cell is vital ...
Biotechnology
Jun 15, 2020
0
120
Researchers from the group of Hans Clevers at the Hubrecht Institute have developed a new genetic tool to label specific genes in human organoids, or mini organs. They used this new method, called CRISPR-HOT, to investigate ...
Cell & Microbiology
Mar 2, 2020
0
482
Therapeutic proteins are protein-based drug candidates bioengineered in the lab for pharmaceutical and clinical applications. Based on their pharmacokinetics, the candidates can be divided into groups that (1) replace a defective ...
Walter and Eliza Hall Institute researchers have made a surprise discovery about how subtle changes in the way cell survival is regulated during embryonic development can have drastic health implications.
Cell & Microbiology
Sep 19, 2018
0
19
A wide range of fetal genetic abnormalities could soon be detected in early pregnancy thanks to a world-first study led by University of South Australia researchers using lab-on-a-chip, non-invasive technology.
Analytical Chemistry
Jul 11, 2018
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4
A small microfluidic device that can separate maternal and fetal cells is being developed to detect genetic abnormalities in early pregnancy through non-invasive blood tests.
Analytical Chemistry
Jun 14, 2018
0
4
Zebrafish embryos are transparent and develop outside the mother's body, enabling scientists to get a detailed view of early development. A research team led by Lila Solnica-Krezel, the Alan A. and Edith L. Wolff Distinguished ...
Cell & Microbiology
May 23, 2018
0
13
The accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments. The Cyclin E and Myc genes are active in the control of cell division. When they mutate ...
Cell & Microbiology
Mar 1, 2018
0
33
Human cancers often have a little recognized ally— the increased size and number of a cell's organelles called the nucleolus. The nucleolus is where ribosomes, the cellular protein factories, are made. Ribosomes can also ...
Cell & Microbiology
Feb 14, 2018
0
5
