News tagged with activator protein
Designer molecule detects tiny amounts of cyanide, then glows
Oct 21, 2009 |
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(PhysOrg.com) -- A small molecule designed to detect cyanide in water samples works quickly, is easy to use, and glows under ultraviolet or "black" light. Although the fluorescent molecule is not yet ready ...
How 'molecular machines' kick start gene activation revealed
Biology /
Nov 06, 2008 |
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How 'molecular machines' inside cells swing into action to activate genes at different times in a cell's life is revealed today in new research published in Molecular Cell.
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In preeclampsia, researchers identify proteins that cause blood vessel damage
Mar 19, 2007 |
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Proteins released by the placenta may damage blood vessels in women with preeclampsia (PE), according to an abstract presented by Yale School of Medicine researchers at the Society for Gynecologic Investigation Conference ...
In Preeclampsia, Researchers Identify Proteins that Cause Blood Vessel Damage
Mar 15, 2007 |
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Proteins released by the placenta may damage blood vessels in women with preeclampsia (PE), according to an abstract presented by Yale School of Medicine researchers at the Society for Gynecologic Investigation Conference ...
Yes-associated protein: Early diagnosis of gastric carcinoma
Sep 17, 2009 |
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Yes-associated protein (YAP) is a type of cellular adaptor protein and transcriptional co-activator. In recent years, some investigators have found YAP to be overexpressed and highly activated in hepatic cancers and mammary ...
Drug mimics low-cal diet to ward off weight gain, boost running endurance
Nov 04, 2008 |
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A drug designed to specifically hit a protein linked to the life-extending benefits of a meager diet can essentially trick the body into believing food is scarce even when it isn't, suggests a new report in the November Cell Me ...
Turn back, wayward axon
Mar 09, 2009 |
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To a growing axon, the protein RGMa is a "Wrong Way" sign, alerting it to head in another direction. As Hata et al. demonstrate in the March 9, 2009 issue of the Journal of Cell Biology, translating that s ...
Biochemical 'On-Switch' Could Solve Protein Purification Challenge
Oct 20, 2009 |
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(PhysOrg.com) -- Drugs based on engineered proteins represent a new frontier for pharmaceutical makers. Even after they discover a protein that may form the basis of the next wonder drug, however, they have ...
Fate in fly sensory organ precursor cells could explain human immune disorder
Jun 21, 2009 |
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(June 21, 2009) - Notch signaling helps determine the fate of a number of different cell types in a variety of organisms, including humans. In an article that appears in the current issue of Nature Cell Biology, researchers at Bay ...
Fat chance: Brown vs. white fat cell specification
May 14, 2008 |
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In the May 15th issue of G&D, Dr. Bruce Spiegelman (Dana Farber Cancer Institute) and colleagues elucidate the molecular pathway that induces cells to become energy-burning brown fat cells as opposed to energy-storing white ...
Blocking signal molecule can prevent growth of large intestine and colon cancer
Sep 23, 2009 |
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By seeing what substances and molecules affect the development of our diseases, we can develop drugs that prevent or cure diseases. In her dissertation at Kalmar University in Sweden, Ann Novotny has found that the signal ...
Mystery solved: Tiny protein-activator responsible for brain cell damage in Huntington disease
Jun 04, 2009 |
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Johns Hopkins brain scientists have figured out why a faulty protein accumulates in cells everywhere in the bodies of people with Huntington's disease (HD), but only kills cells in the part of the brain that controls movement, ...
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