News tagged with active enzyme
IDO2 an active enzyme to target in pancreatic cancer
Dec 01, 2008 |
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An enzyme that is overexpressed in pancreatic cancer cells may hold the key to successfully treating the disease with targeted immunotherapy, researchers from Thomas Jefferson University reported at the 2008 Annual Meeting ...
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Scientists crack mystery of protein's dual function
Dec 13, 2009 |
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Researchers at The Scripps Research Institute have solved a 10-year-old mystery of how a single protein from an ancient family of enzymes can have two completely distinct roles in the body. In addition to providing guidance ...
Synthetic protein mimics structure, function of metalloprotein in nature
Dec 10, 2009 |
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Scientists have designed a synthetic protein that is both a structural model and a functional model of a native protein, nitric-oxide reductase.
Researchers uncover chemical basis for extra 'quality control' in protein production
Dec 09, 2009 |
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December 9, 2009 -Even small errors made by cells during protein production can have profound disease effects, and nature has developed ways to uncover these mistakes and correct them. Though in the case of one essential ...
JAK2 inhibitor demonstrates effective, durable control of myelofibrosis
Dec 07, 2009 |
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A first-in-its class oral medication provides significant and durable relief for patients with a rare, debilitating and lethal bone marrow disorder called myelofibrosis, researchers at The University of Texas M. D. Anderson ...
The hidden lives of proteins
Dec 02, 2009 |
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An important Brandeis study appearing in the December 3 issue of Nature raises the curtain on the hidden lives of proteins at the atomic level. The study reports that for the first time, researchers used x ...
Heart failure linked to gene variant affecting vitamin D activation
Dec 01, 2009 |
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Previous studies have shown a link between low vitamin D status and heart disease. Now a new study shows that patients with high blood pressure who possess a gene variant that affects an enzyme critical to normal vitamin ...
Brown fat cells make 'spare tires' shrink
Dec 01, 2009 |
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(PhysOrg.com) -- Scientists at the University of Bonn have found a new signalling pathway which stimulates the production and function of so-called brown fat cells. They propose using these cells that serve as a "natural ...
Knockouts in human cells point to pathogenic targets
Nov 26, 2009 |
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(PhysOrg.com) -- Whitehead researchers have developed a new approach for genetics in human cells and used this technique to identify specific genes and proteins required for pathogens.
Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer
Nov 22, 2009 |
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Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene. This breakthrough ...
Atomic-level Snapshot Catches Protein Motor in Action (w/ Video)
Nov 20, 2009 |
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(PhysOrg.com) -- The atomic-level action of a remarkable class of ring-shaped protein motors has been uncovered by researchers with the Lawrence Berkeley National Laboratory using a state-of-the-art protein ...
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