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Ganetespib showed activity in KRAS-mutant NSCLC as monotherapy and in combinations

The investigational drug ganetespib, a synthetic second-generation Hsp90 inhibitor, slowed the growth of cancer cells taken from non-small cell lung cancer tumors with a mutation in the KRAS gene. The drug was even more active ...

Medicine & Health / Cancer

created Jan 11, 2012 | popularity not rated yet | comments 0

Common antimicrobial inhibits immune cell function

(Medical Xpress) -- Triclosan, a common antibacterial agent found in many hand soaps and other products, is known to have the added benefit of alleviating allergic skin conditions such as eczema. In a study recently published ...

Medicine & Health / Medications

created Jan 06, 2012 | popularity 5 / 5 (2) | comments 0

Engineers develop more effective MRI contrast agent for cancer detection

Many imaging technologies and their contrast agents — chemicals used during scans to help detect tumors and other problems — involve exposure to radiation or heavy metals, which present potential health risks to ...

Nanotechnology / Bio & Medicine

created Dec 23, 2011 | popularity 4.3 / 5 (4) | comments 1 | with audio podcast

Exploiting Trichoderma: From food security to biotechnology

From improving food security to their use as biotechnology power horses, Trichoderma fungi are increasingly being exploited by industry. Current advances in the field are brought together and highlighted in a special issue ...

Biology / Cell & Microbiology

created Dec 21, 2011 | popularity not rated yet | comments 0

Scientists solve ricin riddle using new technology

A protein that controls how the deadly plant poison and bioweapon ricin kills has finally been identified by a team of Austrian researchers in a new study. With a combination of stem cell biology and modern ...

Biology / Cell & Microbiology

created Dec 20, 2011 | popularity not rated yet | comments 0

Researchers use whole-genome sequencing to monitor evolution of drug resistance in bacteria

(PhysOrg.com) -- Two research groups working independently have come up with two different ways to use whole-genome sequencing to follow the path bacteria take in developing resistance to anti-bacterial drugs. Such research ...

Biology / Biotechnology

created Dec 19, 2011 | popularity not rated yet | comments 0 | with audio podcast report

New test could help track down and prosecute terrorists who use nerve gas and other agents

Scientists are reporting development of a first-of-its-kind technology that could help law enforcement officials trace the residues from terrorist attacks involving nerve gas and other chemical agents back ...

Chemistry / Analytical Chemistry

created Dec 14, 2011 | popularity not rated yet | comments 0

Childhood cancer survivors' exposure to chemotherapy, radiation does not increase risk of birth defects in their childre

A large, retrospective study shows that children of childhood cancer survivors who received prior treatment involving radiation to testes or ovaries and/or chemotherapy with alkylating agents do not have an increased risk ...

Medicine & Health / Cancer

created Dec 12, 2011 | popularity not rated yet | comments 0

Pharmacists crucial in plan for terrorist chemical weapons

Terrorist attacks with chemical weapons are a real possibility, according to a study that appears in the online open access journal, Journal of Pharmacy Practice, published by SAGE. Thanks to their extensive knowledge of tox ...

Chemistry / Other

created Dec 10, 2011 | popularity not rated yet | comments 1

Echocardiography offers the future for infarct size quantification

"Up until now infarct size has only been measured as part of clinical studies and not in routine clinical practice. The reason being that the reference method of gadolinium based contrast agents in MRI is expensive, takes ...

Medicine & Health / Cardiology

created Dec 07, 2011 | popularity not rated yet | comments 0

Researchers develop a way to monitor engineered blood vessels as they grow in patients

Using magnetic resonance imaging (MRI) and nanoparticle technology, researchers from Yale have devised a way to monitor the growth of laboratory-engineered blood vessels after they have been implanted in patients. This advance ...

Medicine & Health / Research

created Nov 30, 2011 | popularity not rated yet | comments 0

Internal skin cancer prevention: Repairing UV damage in the skin

(Medical Xpress) -- Scientists at the Friedrich Miescher Institute for Biomedical Research (FMI) of the Novartis Research Foundation have elucidated the mechanisms underlying the repair of UV-induced damage ...

Medicine & Health / Cancer

created Nov 24, 2011 | popularity not rated yet | comments 0

AMP opposes exclusive licensing of NIH proteomics patent

The Association for Molecular Pathology (AMP) opposed the National Institutes of Health (NIH) proposal to exclusively license the subject matter of a cancer-related proteonomics patent application filed by the Agency. AMP's ...

Medicine & Health / Other

created Nov 22, 2011 | popularity not rated yet | comments 1

Inhaled nanoparticles deliver potent anticancer cocktail to lung tumors and block resistance

(PhysOrg.com) -- An ideal treatment for lung cancer would be one that could be inhaled deep into lung tissue where it would deliver tumor-killing agents that would then largely stay in the lungs, avoiding the toxicities that ...

Nanotechnology / Bio & Medicine

created Nov 21, 2011 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Panel of melanoma mutations opens door to new treatment possibilities

Researchers have developed a new genetic screening tool that will aid in the investigation of possible treatments for patients with melanoma and the unique genetic mutations that may accompany the disease, according to data ...

Medicine & Health / Cancer

created Nov 15, 2011 | popularity 5 / 5 (1) | comments 0