News tagged with alpha synuclein
Study first to link mitochondrial dysfunction and alpha-Synuclein multiplication in human fibroblasts
A new study in the Journal of Parkinson's Disease shows for the first time the effects of α-Synuclein (α-syn) gene multiplication on mitochondrial function and susceptibility to oxidative stress in human tissue ...
Oct 06, 2011 |
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Seeds of destruction in Parkinson's disease: Spread of diseased proteins kills neurons
New research suggests that small "seed" amounts of diseased brain proteins can be taken up by healthy neurons and propagated within them to cause neurodegeneration. The research, published by Cell Press in the October 6 issue ...
Medicine & Health / Neuroscience
Oct 05, 2011 |
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New clue to Parkinson's: Shape of key protein surprises researchers
A new study finds that a protein key to Parkinson's disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging ...
Aug 14, 2011 |
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SUMO defeats protein aggregates that typify Parkinson's disease
A small protein called SUMO might prevent the protein aggregations that typify Parkinson's disease (PD), according to a new study in the July 11, 2011, issue of The Journal of Cell Biology.
Jul 11, 2011 |
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Rare genetic disorder provides unique insight into Parkinson's disease
Massachusetts General Hospital investigators appear to have found the mechanism behind a previously reported link between the rare genetic condition Gaucher disease and the common neurodegenerative disorder Parkinson's disease. ...
Jun 23, 2011 |
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Researchers find new clues about protein linked to Parkinson's disease
Researchers at the Keck School of Medicine of the University of Southern California (USC) have uncovered structural clues about the protein linked to Parkinson's disease (PD), which ultimately could lead to finding a cure ...
Jun 17, 2011 |
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Copper folds protein into precursors of Parkinson's plaques
Researchers at North Carolina State University have figured out how copper induces misfolding in the protein associated with Parkinson's disease, leading to creation of the fibrillar plaques which characterize the disease. ...
Jun 14, 2011 |
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New research reveals unexpected biological pathway in glaucoma
In a study published today in the Proceedings of the National Academy of Sciences (Early Edition ahead of print), a team of researchers from the Kennedy Krieger Institute and four collaborating institutions, identified a new ...
Jan 03, 2011 |
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Key Parkinson's clue could be protein aggregate
(PhysOrg.com) -- Proteins perform almost every function our bodies require for life. But, they also can misbehave in myriad ways. By retracing the history of each abnormal reaction, biochemists aim to determine ...
Nov 03, 2010 |
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Researchers Identify Gene Mutations Underlying Risk for Most Common Form of Parkinson's Disease
(PhysOrg.com) -- Two genes containing mutations known to cause rare familial forms of parkinsonism are also associated with the more common, sporadic form of the disease where there is no family history, researchers have ...
Nov 17, 2009 |
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Researchers Suggest New Approach in Development Efforts for Parkinson’s Therapeutics
(PhysOrg.com) -- Researchers outline today a new approach in the potential development of drugs to counter a cellular defect that triggers Parkinson’s and other diseases.
Jul 14, 2009 |
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Protein protects neurons in brain from damage due to inflammation
A research team from the University of California, San Diego School of Medicine and the Salk Institute for Biological Studies in La Jolla has identified a protein in the brain of mice that protects neurons from excessive ...
Apr 02, 2009 |
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Study finds link between Parkinson's disease genes and manganese poisoning
A connection between genetic and environmental causes of Parkinson's disease has been discovered by a research team led by Aaron D. Gitler, PhD, Assistant Professor in the Department of Cell and Developmental ...
Feb 01, 2009 |
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