News tagged with amantadine
Amantadine
Amantadine is the organic compound known formally as 1-adamantylamine or 1-aminoadamantane. The molecule consists of adamantane backbone that has an amino group substituted at one of the four methyne positions. This pharmaceutical is sold under the name Symmetrel for use both as an antiviral and an antiparkinsonian drug. Rimantadine is a closely related derivative of adamantane with similar biological properties.
Apart from medical uses, this compound is useful as a building block, allowing the insertion of an adamantyl group.
According to the US Centers for Disease Control and Prevention, 100% of seasonal H3N2 and 2009 pandemic flu samples tested have shown resistance to adamantanes, and amantadine is no longer recommended for treatment of influenza. Additionally, its effectiveness as an antiparkinsonian drug is controversial, with a 2003 Cochrane Review concluding that it was ineffective for this purpose.
For more information about Amantadine, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
Antidepressants linked to cataract risk -- Parkinson's drug may cause corneal damage
This month's Ophthalmology, the journal of the American Academy of Ophthalmology, includes new studies on links between eye diseases and two widely-prescribed drugs: SSRI (selective serotonin reuptake inhibitor) antidepressants, and am ...
Medicine & Health / Medications
Jun 01, 2010 |
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Chemists discover how antiviral drugs bind to and block flu virus
Antiviral drugs block influenza A viruses from reproducing and spreading by attaching to a site within a proton channel necessary for the virus to infect healthy cells, according to a research project led ...
Feb 03, 2010 |
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CDC: Mild flu season apparently winding down
(AP) -- The flu season is winding down and turning out to be one of the mildest in years, according to data from the U.S. Centers for Disease Control and Prevention.
Apr 07, 2009 |
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Search results for amantadine
P7 protein resistance mutations identified; represent drug targets for hepatitis C virus
British researchers have identified specific resistance mutations for two classes of p7 inhibitor, which may explain their lack of effectiveness in clinical trials combined with current standard of care. Study results support ...
Jun 28, 2011 |
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Researchers study flu proteins in-depth to identify virus vulnerabilities
Each year, people everywhere prepare for flu season. Some will get the flu vaccine, some take vitamin supplements, some launch a vigorous handwashing campaign, while others take an entirely different approach: ...
Feb 14, 2011 |
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Putting a bull's-eye on the flu: Detailing influenza's structure for drug targeting (w/ Video)
Beating the flu is already tough, but it has become even harder in recent years – the influenza A virus has mutated so that two antiviral drugs don't slow it down anymore.
Oct 21, 2010 |
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Triple-combo drug shows promise against antiviral-resistant H1N1, researcher says (w/ Video)
An experimental drug cocktail that includes three prescriptions now widely available offers the best hope in developing a single agent to treat drug-resistant H1N1 swine flu, says a virology researcher in the University of ...
Oct 27, 2009 |
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Major flu strain resistant to widely used antiviral drug
One of the major strains of the influenza virus this season has become resistant to Tamiflu - rendering the mainstay antiviral drug all but impotent and creating tough treatment options for patients who come down with the ...
Jan 15, 2009 |
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Study: Quick responses to influenza outbreaks reduces illness and death
Influenza outbreaks were shorter and resulted in fewer cases and fewer deaths at long-term care facilities that started residents on preventive antiviral medications within five days of the first case, compared to those that ...
Jun 10, 2008 |
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Chemists track how drug changes, blocks flu virus
An anti-virus drug attacks influenza A by changing the motion and structure of a proton channel necessary for the virus to infect healthy cells, according to a recently published research paper by two Iowa ...
Feb 01, 2008 |
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Penn researchers discover new target for preventing and treating flu
Emerging subtypes of influenza A virus hold the potential to initiate a world-wide epidemic in the next few years, according to World Health Organization officials. However, almost all type A influenza viral ...
Jan 30, 2008 |
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Cough medicine fights dyskinesias in Parkinson's
A cough suppressant and a drug tested as a schizophrenia therapy curb the involuntary movements that are disabling side effects of taking the Parkinson's disease medication levodopa, Portland scientists have found.
Nov 07, 2007 |
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WHO data confirms low level of resistance to Tamiflu
New data published by the World Health Organisation (WHO) has confirmed a low frequency of resistance to Tamiflu (oseltamivir) over 3 influenza seasons (2003 – 2006).
Medicine & Health / Medications
May 09, 2007 |
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List of search results for amantadine
