News tagged with angiogenesis
Essential protein for the formation of new blood vessels identified
New research explains how cells regulate their bonds during the development of new blood vessels. For the first time, the role of the protein Raf-1 in determining the strength of the bond between cells has ...
Jan 17, 2012 |
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Blood protein EPO involved in origin and spread of cancer
Researchers at the Swedish medical university Karolinska Institutet have demonstrated that a growth hormone, PDGF-BB, and the blood protein EPO are involved in the development of cancer tumours and that they combine to help ...
Dec 05, 2011 |
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Combination therapy shows potent tumor growth inhibition in preclinical studies
Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC ...
Nov 13, 2011 |
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Scientists identify a key molecule that blocks abnormal blood vessel growth in tumors
A new and better understanding of blood vessel growth and vascular development (angiogenesis) in cancer has been made possible by research carried out by a team of scientists from Moffitt Cancer Center, the University of ...
Sep 21, 2011 |
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New model for studying germ cell tumors in testes enlists embryonic stem cells
A team of researchers from Spain and Switzerland have developed a new model for studying the development of testicular germ cell tumors by transplanting embryonic stem cells into the seminiferous tubules in mouse models, ...
Jul 11, 2011 |
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New molecular pathway regulating angiogenesis may fight retinal disease, cancers
Scientists identify in the journal Nature a new molecular pathway used to suppress blood vessel branching in the developing retina – a finding with potential therapeutic value for fighting diseases of the retina and a ...
May 29, 2011 |
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Parsley, celery carry crucial component for fight against breast cancer, researcher finds
Parsley is usually used as a decorative accent to a scrumptious meal, but don't set it aside just yet. In a new study, a University of Missouri researcher has found that a compound in parsley and other plant products, including ...
May 09, 2011 |
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Compound used to block cholesterol could also kill breast cancer, researcher finds
A University of Missouri researcher believes there could be a new drug compound that could kill breast cancer cells. The compound might also help with controlling cholesterol.
Feb 22, 2011 |
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Immune system may impact tumor blood supply
Scientists at the Dana-Farber Cancer Institute may have uncovered a mechanism for blocking tumor angiogenesis that involves the patient’s immune system, according to findings published in Cancer Research, a journal of the ...
Dec 15, 2010 |
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Morphine blocks tumor growth
Current research suggests that taking morphine can block new blood vessel and tumor growth. The related report by Koodie et al, "Morphine suppresses tumor angiogenesis through a HIF1α/p38MAPK pathway," appears in the ...
Jul 28, 2010 |
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Noninvasive MR imaging of blood vessel growth in tumors using nanosized contrast agents
Formation of new blood vessels, also known as angiogenesis, is crucial for sustained tumor growth and cancer metastasis. Recently, clinically available therapies to suppress the growth of these vessels have been available ...
Jul 23, 2010 |
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Spanish gene expression data promise targeting of anti-angiogenesis treatment
Analyzing the expression of particular genes in lung cancers could soon allow researchers to identify groups of patients who are likely to benefit most from treatment with angiogenesis-inhibitor drugs, a Spanish team reports.
Apr 29, 2010 |
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Researchers uncover novel genetic pathway responsible for triggering vascular growth
Most solid cancers can't grow beyond a limited size without an adequate blood supply and supporting vascular network. Because of this, cancer researchers have sought to understand how a tumor's vascular network develops—and, ...
Apr 04, 2010 |
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Bone marrow cell transplants to benefit those with heart disease
Two studies published in the latest issue of Cell Transplantation (18:12) may lead to new treatments for the treatment of heart diseases. The first study, carried out by a team of Brazilian researchers, found that cell t ...
Feb 24, 2010 |
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A study reveals how respiratory tubes and capillaries form
Scientists at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC report on the formation of the small-diameter respiratory tubes of the fly Drosophila, a process that resembles the development ...
Feb 09, 2010 |
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Angiogenesis
Angiogenesis is the physiological process involving the growth of new blood vessels from pre-existing vessels. Though there has been some debate over terminology, vasculogenesis is the term used for spontaneous blood-vessel formation, and intussusception is the term for the formation of new blood vessels by the splitting of exisiting ones.
Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and in granulation tissue. However, it is also a fundamental step in the transition of tumors from a dormant state to a malignant one, leading to the use of angiogenesis inhibitors. The identification of an angiogenic diffusible factor derived from tumors was made initially by Greenblatt and Shubik in 1968.
For more information about Angiogenesis, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
