Related topics: bacteria , infectious diseases , antibiotic resistance
Antibiotic
hideIn common usage, an antibiotic (from the Ancient Greek: ἀντί – anti, "against", and βίος – bios, "life") is a substance or compound that kills bacteria or inhibits their growth. Antibiotics belong to the broader group of antimicrobial compounds, used to treat infections caused by microorganisms, including fungi and protozoa.
The term "antibiotic" was coined by Selman Waksman in 1942 to describe any substance produced by a microorganism that is antagonistic to the growth of other microorganisms in high dilution. This original definition excluded naturally occurring substances that kill bacteria but are not produced by microorganisms (such as gastric juice and hydrogen peroxide) and also excluded synthetic antibacterial compounds such as the sulfonamides. Many antibiotics are relatively small molecules with a molecular weight less than 2000 Da.[citations needed]
With advances in medicinal chemistry, most antibiotics are now semisynthetic—modified chemically from original compounds found in nature, as is the case with beta-lactams (which include the penicillins, produced by fungi in the genus Penicillium, the cephalosporins, and the carbapenems). Some antibiotics are still produced and isolated from living organisms, such as the aminoglycosides, and others have been created through purely synthetic means: the sulfonamides, the quinolones, and the oxazolidinones. In addition to this origin-based classification into natural, semisynthetic, and synthetic, antibiotics may be divided into two broad groups according to their effect on microorganisms: those that kill bacteria are bactericidal agents, while those that only impair bacterial growth are known as bacteriostatic agents.
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News tagged with antibiotics
Novel nanotechnology heals abscesses caused by resistant staph bacteria
Nanotechnology / Bio & Medicine
Dec 22, 2009 |
4.3 / 5 (3) |
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Researchers at the Albert Einstein College of Medicine of Yeshiva University have developed a new approach for treating and healing skin abscesses caused by bacteria resistant to most antibiotics. The study ...
Disinfectants may promote growth of superbugs
3 hours ago |
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Using disinfectants could cause bacteria to become resistant to antibiotics as well as the disinfectant itself, according to research published in the January issue of Microbiology. The findings could have important implic ...
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First case of highly drug-resistant TB found in US
18 hours ago |
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(AP) -- It started with a cough, an autumn hack that refused to go away.
New study shows rise in drug resistance of dangerous infection in US hospitals
Dec 23, 2009 |
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A new study in the journal Infection Control and Hospital Epidemiology reports a surge in drug-resistant strains of Acinetobacter, a dangerous type of bacteria that is becoming increasingly common in U.S. hospitals. This ...
Soil studies reveal rise in antibiotic resistance
Dec 23, 2009 |
3 / 5 (1) |
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Antibiotic resistance in the natural environment is rising despite tighter controls over our use of antibiotics in medicine and agriculture, Newcastle University scientists have found.
Deadly infection more common than realized
Dec 22, 2009 |
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Staphylococcus aureus causes far more serious infections than previously realised, with more than 3,000 Swedes affected every year, reveals a thesis from the Sahlgrenska Academy at the University of Gothenburg, Sweden.
Feds mull regulating drugs in water
Dec 22, 2009 |
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(AP) -- Federal regulators under President Barack Obama have sharply shifted course on long-standing policy toward pharmaceutical residues in the nation's drinking water, taking a critical first step toward regulating some ...
New, virulent strain of MRSA poses renewed antibiotic resistance concerns
Dec 22, 2009 |
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The often feared and sometimes deadly infections caused by MRSA - methicillin-resistant Staphylococcus aureus - are now moving out of hospitals and emerging as an even more virulent strain in community settings and on ath ...
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