News tagged with antitumor agent
Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of the Opioid Growth Factor (OGF, [Met5]-enkephalin), a clinically important antitumor agent, is ...
Apr 23, 2009 |
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Microfluidic Device Mimics Tumor Microenvironment, Helps Drug Discovery Efforts
One of the challenges that cancer researchers face in designing new antitumor agents is that of predicting how drug molecules will behave in the complex microenvironment that surrounds a tumor. In particular, tumors create ...
Feb 23, 2009 |
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Search results for antitumor agent
Everolimus prolongs progression-free survival for patients with neuroendocrine tumors
Combination treatment with everolimus, an inhibitor of the mammalian target rapamycin (mTOR), and octreotide has shown to improve progression-free survival for patients with advanced neuroendocrine tumors and a history of ...
Nov 29, 2011 |
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Combination therapy shows potent tumor growth inhibition in preclinical studies
Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC ...
Nov 13, 2011 |
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Benefits of radionuclide therapy for neuroendocrine tumors
According to new Dutch research featured in the September issue of The Journal of Nuclear Medicine, a peptide receptor radiolabeled therapy (PRRT), [177Lu-DOTA0,Tyr3]Octreotate (177Lu-octreotate) , is effective not only i ...
Sep 20, 2011 |
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Low-dose naltrexone (LDN): Tricking the body to heal itself
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered the mechanism by which a low dose of the opioid antagonist naltrexone (LDN), an agent used clinically (off-label) ...
Sep 02, 2011 |
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Medicinal chemists modify sea bacteria byproduct for use as potential cancer drug
University of Florida researchers have modified a toxic chemical produced by tiny marine microbes and successfully deployed it against laboratory models of colon cancer.
Aug 31, 2011 |
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Low dose naltrexone (LDN): Harnessing the body's own chemistry to treat human ovarian cancer
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that a low dose of the opioid antagonist naltrexone (LDN) has an extraordinarily potent antitumor effect on human ...
Jul 12, 2011 |
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New class of antiangiogenesis drugs identified
Massachusetts General Hospital (MGH) researchers have discovered the first of an entirely new class of antiangiogenesis drugs agents that interfere with the development of blood vessels. In a report in Proceedings of ...
Jul 01, 2011 |
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Molecule Nutlin-3a activates a signal inducing cell death and senescence in primary brain tumors
Researchers of Apoptosis and Cancer Group of the Bellvitge Biomedical Research Institute (IDIBELL) have found that a small molecule, Nutlin-3a, an antagonist of MDM2 protein, stimulates the signalling pathway of another protein, ...
Apr 20, 2011 |
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Small molecules inhibit growth of human tumor cells
Researchers from the Cancer Institute at NYU Langone Medical Center have identified three novel small molecules that interrupt a crucial cellular communication pathway that regulates many aspects of development ...
Apr 13, 2011 |
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Scientists find potential benefit of hypericin for recurrent brain tumors
Researchers have found that a synthetic version of hypericin, a compound naturally found in St. John's wort, may be a promising treatment for patients with recurrent malignant brain tumors. Their findings were published online ...
Apr 11, 2011 |
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List of search results for antitumor agent