News tagged with antitumor agent

Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals

Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of the Opioid Growth Factor (OGF, [Met5]-enkephalin), a clinically important antitumor agent, is ...

Medicine & Health / Research

created Apr 23, 2009 | popularity 3 / 5 (1) | comments 0

Microfluidic Device Mimics Tumor Microenvironment, Helps Drug Discovery Efforts

One of the challenges that cancer researchers face in designing new antitumor agents is that of predicting how drug molecules will behave in the complex microenvironment that surrounds a tumor. In particular, tumors create ...

Chemistry / Biochemistry

created Feb 23, 2009 | popularity not rated yet | comments 1




Search results for antitumor agent


Everolimus prolongs progression-free survival for patients with neuroendocrine tumors

Combination treatment with everolimus, an inhibitor of the mammalian target rapamycin (mTOR), and octreotide has shown to improve progression-free survival for patients with advanced neuroendocrine tumors and a history of ...

Medicine & Health / Cancer

created Nov 29, 2011 | popularity not rated yet | comments 0 | with audio podcast

Combination therapy shows potent tumor growth inhibition in preclinical studies

Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC ...

Medicine & Health / Cancer

created Nov 13, 2011 | popularity not rated yet | comments 0

Benefits of radionuclide therapy for neuroendocrine tumors

According to new Dutch research featured in the September issue of The Journal of Nuclear Medicine, a peptide receptor radiolabeled therapy (PRRT), [177Lu-DOTA0,Tyr3]Octreotate (177Lu-octreotate) , is effective not only i ...

Medicine & Health / Cancer

created Sep 20, 2011 | popularity 5 / 5 (2) | comments 1

Low-dose naltrexone (LDN): Tricking the body to heal itself

Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered the mechanism by which a low dose of the opioid antagonist naltrexone (LDN), an agent used clinically (off-label) ...

Medicine & Health / Research

created Sep 02, 2011 | popularity 5 / 5 (3) | comments 0

Medicinal chemists modify sea bacteria byproduct for use as potential cancer drug

University of Florida researchers have modified a toxic chemical produced by tiny marine microbes and successfully deployed it against laboratory models of colon cancer.

Medicine & Health / Cancer

created Aug 31, 2011 | popularity not rated yet | comments 0 | with audio podcast

Low dose naltrexone (LDN): Harnessing the body's own chemistry to treat human ovarian cancer

Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that a low dose of the opioid antagonist naltrexone (LDN) has an extraordinarily potent antitumor effect on human ...

Medicine & Health / Cancer

created Jul 12, 2011 | popularity 5 / 5 (2) | comments 0

New class of antiangiogenesis drugs identified

Massachusetts General Hospital (MGH) researchers have discovered the first of an entirely new class of antiangiogenesis drugs – agents that interfere with the development of blood vessels. In a report in Proceedings of ...

Medicine & Health / Research

created Jul 01, 2011 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Molecule Nutlin-3a activates a signal inducing cell death and senescence in primary brain tumors

Researchers of Apoptosis and Cancer Group of the Bellvitge Biomedical Research Institute (IDIBELL) have found that a small molecule, Nutlin-3a, an antagonist of MDM2 protein, stimulates the signalling pathway of another protein, ...

Medicine & Health / Cancer

created Apr 20, 2011 | popularity not rated yet | comments 0

Small molecules inhibit growth of human tumor cells

Researchers from the Cancer Institute at NYU Langone Medical Center have identified three novel small molecules that interrupt a crucial cellular communication pathway that regulates many aspects of development ...

Medicine & Health / Cancer

created Apr 13, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists find potential benefit of hypericin for recurrent brain tumors

Researchers have found that a synthetic version of hypericin, a compound naturally found in St. John's wort, may be a promising treatment for patients with recurrent malignant brain tumors. Their findings were published online ...

Medicine & Health / Cancer

created Apr 11, 2011 | popularity not rated yet | comments 0


List of search results for antitumor agent