News tagged with apoptosis
How proteins talk to each other: Caspase-3 cleaves in unforeseen ways
Sep 21, 2009 |
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Investigators at Burnham Institute for Medical Research have identified novel cleavage sites for the enzyme caspase-3 (an enzyme that proteolytically cleaves target proteins). Using an advanced proteomic technique called ...
Roles of S100A2 and p63 in the carcinogenesis of esophageal squamous cell carcinoma
Sep 17, 2009 |
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As a member of the S100 family, S100A2 is considered a candidate tumor-suppressor gene. Recently, p63 gene, a new member of the p53 gene family, has been studied in the fields of tumorigenesis, cell apoptosis and tissue growth. ...
New function for the protein Bcl-xL: It prevents bone breakdown
Sep 14, 2009 |
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In blood cells, the protein Bcl-xL has a well-characterized role in preventing cell death by a process known as apoptosis. However, its function(s) in osteoclasts, cells that slowly breakdown bone (a process known as resorption), ...
How mitochondria get their membranes bent
Jun 24, 2009 |
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Underneath their smooth surface mitochondria harbor an elaborately folded inner membrane. It holds a multitude of bottleneck like invaginations, which expand into elongated cavities. Now researchers have identified two proteins ...
A potential drug for liver carcinoma
May 22, 2009 |
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Looking for efficient anti-tumor drugs is a hot research area. Chrysin (5,7-dihydroxy flavone), a natural widely-distributed flavonoid, has been reported to have many different biological activities such as anti-oxidant, ...
Alzheimer's disease therapeutic prevents long-term damage from TBI in pre-clinical studies
Mar 15, 2009 |
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A class of Alzheimer's disease drugs currently studied in clinical trials appears to reduce damage caused by traumatic brain injury in animals, researchers at Georgetown University Medical Center report in an upcoming advance ...
