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Asthma

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Asthma is a chronic inflammation of the lungs in which the airways (bronchi) are reversibly narrowed. Asthma affects 7% of the population, and 300 million worldwide. During attacks (exacerbations), the smooth muscle cells in the bronchi constrict, and the airways become inflamed and swollen. Breathing becomes difficult, and asthma causes 4,000 deaths a year in the U.S. Attacks can be prevented by avoiding triggering factors and by drug treatment. Drugs are used for acute attacks, commonly inhaled β2-agonists. In more serious cases, drugs are used for long-term prevention, starting with inhaled corticosteroids, and then long-acting β2-agonists if necessary. Leukotriene antagonists are less effective than corticosteroids but have no side effects. Monoclonal antibodies such as mepolizumab and omalizumab are sometimes effective. Prognosis is good with treatment.

In contrast to chronic obstructive pulmonary disease and chronic bronchitis, the inflammation of asthma is reversible. In contrast to emphysema, asthma affects the bronchi, not the alveoli.

The National Heart, Lung and Blood Institute defines asthma as a common chronic disorder of the airways characterized by variable and recurring symptoms, airflow obstruction, bronchial hyperresponsiveness (bronchospasm), and an underlying inflammation.

Public attention in the developed world has recently focused on asthma because of its rapidly increasing prevalence, affecting up to one in four urban children.

For more information about Asthma, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with asthma


Genetic variant may control lung function and risk of COPD

Medicine & Health / Diseases

created Dec 17, 2009 | popularity not rated yet | comments 0

Researchers have discovered evidence that suggests a genetic variant may be associated with better preserved lung function among children with asthma and adults who smoke, according to a new study funded by the National Heart, ...


Better education associated with improved asthma

Medicine & Health / Diseases

created Dec 17, 2009 | popularity not rated yet | comments 0

Individuals with more education suffer less from asthma. Researchers writing in BioMed Central's open access journal Respiratory Research have found that having less than 12 years of formal schooling is associated with w ...





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New genes for lung disease discovered

Medicine & Health / Genetics

created Dec 13, 2009 | popularity 5 / 5 (3) | comments 0

(PhysOrg.com) -- Scientists have discovered five genetic variants that are associated with the health of the human lung. The research by an international consortium of 96 scientists from 63 centres in Europe and Australia ...


Study unveils potential genetic links to lung disease risk

Medicine & Health / Genetics

created Dec 14, 2009 | popularity not rated yet | comments 0

A new study involving data from more than 20,000 individuals has uncovered several DNA sequences linked to impaired pulmonary function. The research, an analysis that combined the results of several smaller studies, provides ...


Breakthrough on causes of inflammatory bowel disease

Medicine & Health / Diseases

created Dec 17, 2009 | popularity 4.3 / 5 (4) | comments 0

New research by the University of Adelaide could help explain why some people are more prone to Crohn's disease, ulcerative colitis and other autoimmune diseases.


Swine flu vaccine now plentiful in half the states

Medicine & Health / Medications

created Dec 16, 2009 | popularity not rated yet | comments 0

(AP) -- After weeks of shortages, swine flu vaccine is plentiful enough that nearly half the states now say everyone can get it, not just people in high-risk groups.


Immune cell activity linked to worsening COPD

Medicine & Health / Diseases

created Dec 15, 2009 | popularity not rated yet | comments 0

A new study links chronic obstructive pulmonary disease, or COPD, with increased activity of cells that act as sentinels to activate the body's immune system.



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