News tagged with atorvastatin
Atorvastatin
Atorvastatin (INN) ( /əˌtɔrvəˈstætən/), sold by Pfizer under the trade name Lipitor, is a member of the drug class known as statins, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.
Atorvastatin was first synthesized in 1985 by Bruce Roth while working at Parke-Davis Warner-Lambert Company (now Pfizer). With 2008 sales of US$12.4 billion, Lipitor was the top-selling branded pharmaceutical in the world. U.S. patent protection was scheduled to expire in June 2011. However, Pfizer made an agreement with Ranbaxy Laboratories to delay the generic launch in the U.S. until November 30, 2011.
For more information about Atorvastatin, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
US seeks injunction on Indian drug firm Ranbaxy
US officials sought a "groundbreaking" injunction against Indian drug giant Ranbaxy on Wednesday, saying the maker of the first generic version of cholesterol-lowering Lipitor has failed to meet US safety guidelines.
Medicine & Health / Medications
Jan 26, 2012 |
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0
Study finds statin costs 400 percent higher in US compared to UK
In the United States, the cost paid for statins (drugs to lower cholesterol) in people under the age of 65 who have private insurance is approximately 400 percent higher than comparable costs paid by the government in the ...
Medicine & Health / Medications
Jan 05, 2012 |
3.7 / 5 (3) |
12
With new generic rivals, Lipitor's sales halved
Sales of cholesterol blockbuster Lipitor plunged by half barely a week after the world's top-selling drug got its first U.S. generic competition, new data show.
Medicine & Health / Medications
Dec 20, 2011 |
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3
US approves India's Ranbaxy to make generic Lipitor
Indian pharmaceutical giant Ranbaxy won US regulatory approval to make the first generic version of cholesterol lowering drug Lipitor, a Pfizer product whose patent expired Wednesday.
Medicine & Health / Medications
Dec 01, 2011 |
5 / 5 (1) |
0
Pfizer's blockbuster drug Lipitor goes generic
Pfizer's patent on the best-selling drug of all-time, the cholesterol-lowering medication Lipitor, expired on Wednesday, opening the path to generic competitors for America's most popular medication.
Medicine & Health / Medications
Nov 30, 2011 |
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1
Two statin drugs similarly effective in reversing coronary heart disease
Maximum doses of Crestor (rosuvastatin) or Lipitor (atorvastatin) are similarly effective in reversing the buildup of cholesterol plaques in the coronary artery walls (atherosclerosis) after 24 months of treatment, according ...
Medicine & Health / Cardiology
Nov 15, 2011 |
3 / 5 (2) |
2
Statin therapy fails to slow progression of atherosclerosis in pediatric lupus patients
Atorvastatin therapy was found to be ineffective in reducing atherosclerosis progression in children and adolescents with systemic lupus erythematosus (SLE). Results of the Atherosclerosis Prevention in Pediatric Lupus Erythematosus ...
Oct 27, 2011 |
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0
Statins reduce deaths from infection and respiratory illness, eight years on from trial
The death rate among patients prescribed a statin in a major trial that ended in 2003 is still lower than those given a placebo, even though most participants in both groups have been taking statins ever since. ASCOT, the ...
Medicine & Health / Cardiology
Aug 28, 2011 |
5 / 5 (2) |
0
Type 2 diabetes linked to higher risk of stroke and CV problems; metabolic syndrome isn't
Among patients who have had an ischemic stroke or transient ischemic attack (TIA), type 2 diabetes was associated with an increased risk of recurrent stroke or cardiovascular events, but metabolic syndrome was not, according ...
Medicine & Health / Neuroscience
Jun 13, 2011 |
5 / 5 (1) |
0
Statins don't lower risk of pneumonia in elderly
Taking popular cholesterol-lowering statin drugs, such as Lipitor (atorvastatin), does not lower the risk of pneumonia. That's the new finding from a study of more than 3,000 Group Health patients published online on June ...
Jun 17, 2009 |
4 / 5 (1) |
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