Even intense exercise by astronauts cannot compensate for muscle atrophy caused by microgravity. Atrophy occurs, in part, by way of an underlying mechanism that regulates calcium uptake. Recent research has shown exposure ...
Space Exploration
Apr 17, 2024
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8
To carry out all of life's functions, proteins must be produced from instructions carried by genes within DNA and delivered to the cell's protein-making machinery by messenger RNA.
Cell & Microbiology
Nov 24, 2023
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22
Researchers from Tokyo Metropolitan University have shown that the protein Musashi-2 (Msi2) plays a key role in the regulation of mass and metabolic processes in skeletal muscle. They studied mice with the Msi2 gene knocked ...
Cell & Microbiology
Sep 11, 2023
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8
A team of scientists from A*STAR's Genome Institute of Singapore (GIS) and the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) has made an important breakthrough in the fight against RNA viruses ...
Cell & Microbiology
Aug 2, 2023
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73
Scientists from Tokyo Metropolitan University have discovered that a protein called platelet-derived growth factor subunit B (PDGF-B) is continuously secreted from skeletal muscle cells and helps to repair muscles by encouraging ...
Cell & Microbiology
Jan 16, 2023
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8
WNT signaling is crucial for the development of organisms and the maintenance of tissue homeostasis, since the WNT messengers are involved in a variety of cellular functions. In skeletal muscle, for example, they can increase ...
Cell & Microbiology
Dec 13, 2022
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10
For several years now, the CRISPR/Cas9 gene scissors have been causing a sensation in science and medicine. This new tool of molecular biology has its origins in an ancient bacterial immune system. It protects bacteria from ...
Biotechnology
Nov 25, 2022
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178
Researchers from Tokyo Metropolitan University have developed a way to characterize the force generated by contracting myotubes, precursors to skeletal muscle fiber, combining electrostimulation and analysis of wrinkles in ...
Biochemistry
Sep 5, 2022
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95
Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, ...
Molecular & Computational biology
Mar 14, 2022
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288
Many kids dream of growing up to be astronauts; but the downside of spending extended amounts of time in low gravity is that astronauts' muscles tend to shrink and weaken through disuse. Now, researchers from Japan have identified ...
Molecular & Computational biology
Jul 8, 2021
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17
Atrophy is the partial or complete wasting away of a part of the body. Causes of atrophy include poor nourishment, poor circulation, loss of hormonal support, loss of nerve supply to the target organ, disuse or lack of exercise or disease intrinsic to the tissue itself. Hormonal and nerve inputs that maintain an organ or body part are referred to as trophic.
Atrophy is a general physiological process of reabsorption and breakdown of tissues, involving apoptosis on a cellular level. When it occurs as a result of disease or loss of trophic support due to other disease, it is termed pathological atrophy, although it can be a part of normal body development and homeostasis as well.
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