News tagged with bcl 2
New therapeutic target for melanoma identified
Apr 16, 2009 |
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A protein called Mcl-1 plays a critical role in melanoma cell resistance to a form of apoptosis called anoikis, according to research published this week in Molecular Cancer Research.
New clues about mitochondrial 'growth spurts'
Mar 02, 2009 |
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Mitochondria are restless, continually merging and splitting. But contrary to conventional wisdom, the size of these organelles depends on more than fusion and fission, as Berman et al. show. Mitochondrial ...
Search results for bcl 2
New function for the protein Bcl-xL: It prevents bone breakdown
Sep 14, 2009 |
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In blood cells, the protein Bcl-xL has a well-characterized role in preventing cell death by a process known as apoptosis. However, its function(s) in osteoclasts, cells that slowly breakdown bone (a process known as resorption), ...
Researchers turn cancer friend into cancer foe
Oct 07, 2008 |
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Burnham Institute for Medical Research today announced that scientists have created a peptide that binds to Bcl-2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer. ...
Chemosensitivity of cancer cells depends on their protein dependency
Oct 26, 2009 |
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Two different anti-apoptotic proteins support cancer cell survival via an identical mechanism, yet differ in their sensitivity to chemotherapeutic drugs, report Brunelle et al. The study will be published ...
Penn researchers discover how key protein stops inflammation
Aug 08, 2007 |
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Researchers at the University of Pennsylvania School of Medicine recently identified how a regulatory protein called Bcl-3 helps to control the body’s inflammation response to infection by interfering a critical biochemical ...
Cancer cell 'bodyguard' turned into killer
Nov 25, 2008 |
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If you're a cancer cell, you want a protein called Bcl-2 on your side because it decides if you live or die. It's usually a trusted bodyguard, protecting cancer cells from programmed death and allowing them to grow and form ...
New use for a cell toxin found to inhibit survival proteins in cancer cells
Jul 11, 2007 |
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A chemically-modified version of a mitochondrial toxin long used to control species of invasive fish in lakes has been found to selectively inhibit two "survival proteins” in cancer cells. The research is a first step toward ...
New cancer target for non-Hodgkin's lymphoma
Nov 22, 2009 |
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Physician-scientists from Weill Cornell Medical College have discovered a molecular mechanism that may prove to be a powerful target for the treatment of non-Hodgkin's lymphoma, a type of cancer that affects lymphocytes, ...
New research provides hope for childhood cancer sufferers
Jul 20, 2007 |
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Dr Richard Lock, Head of the Leukaemia Biology Program at the Children’s Cancer Institute Australia for Medical Research, Sydney, along with collaborators from the Childrens Hospital Los Angeles and University of Southern ...
Blood's clotting cells harbor 'ticking time bombs'
Mar 22, 2007 |
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Fragments of cells in the blood known as platelets—which form blood clots and assist in wound healing—have internal “clocks” that act like ticking time bombs, predetermining their death from the moment they are born, according ...
New research provides hope for childhood cancer sufferers
Jul 16, 2007 |
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Scientists investigating drug therapies for children with Acute Lymphoblastic Leukaemia (ALL) have presented new data demonstrating for the very first time that a small molecule called ABT-737 can increase the effectiveness ...
List of search results for bcl 2
