News tagged with bcl 2
Molecular discovery suggests new strategy to fight cancer drug resistance
Scientists at Dana-Farber Cancer Institute have found a way to disable a common protein that often thwarts chemotherapy treatment of several major forms of cancer.
Jun 20, 2010 |
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Cancer: Trapping the escape artist
Cancer uses devious means to evade treatment and survive. One prime example is the way tumors express anti-cell death (anti-apoptotic) proteins to resist chemotherapy and radiation. However, the Pellecchia laboratory at Sanford-Burnham ...
May 11, 2010 |
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New therapeutic target for melanoma identified
A protein called Mcl-1 plays a critical role in melanoma cell resistance to a form of apoptosis called anoikis, according to research published this week in Molecular Cancer Research.
Apr 16, 2009 |
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New clues about mitochondrial 'growth spurts'
Mitochondria are restless, continually merging and splitting. But contrary to conventional wisdom, the size of these organelles depends on more than fusion and fission, as Berman et al. show. Mitochondrial ...
Mar 02, 2009 |
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Search results for bcl 2
Exercise triggers beneficial cellular recycling: study
Everyone knows exercise is good for you. We’re told time spent on the treadmill can reduce our risk of diabetes, cancer, and cardiovascular disorders. But exactly how exercise provides this protection ...
Jan 18, 2012 |
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Cell death researchers identify new Achilles heel in acute myeloid leukemia
Melbourne researchers have discovered that acute myeloid leukaemia (AML), an aggressive blood cancer with poor prognosis, may be susceptible to medications that target a protein called Mcl-1.
Jan 17, 2012 |
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Researchers to publish paper in Molecular Cancer journal
(Medical Xpress) -- Erxi Wu, assistant professor of pharmaceutical sciences, and Fengfei Wang, research associate in pharmaceutical sciences, co-wrote the article, "β2-adrenoceptor blockage induces G1/S phase arrest ...
Dec 07, 2011 |
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Research predicts how cancers will respond to chemo, rewrites old theory of why chemo works
Challenging a half-century-old theory about why chemotherapy agents target cancer, scientists at Dana-Farber Cancer Institute have devised a test that can predict how effective the drugs will be by determining whether a patient's ...
Oct 27, 2011 |
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Tea epigallocatechin-3-gallate inhibits cell proliferation in breast cancer patients
(Medical Xpress) -- Erxi Wu, assistant professor of pharmaceutical sciences, and Fengfei Wang, research associate of pharmaceutical sciences, co-wrote the article, "Anti-cancer activities of tea epigallocatechin-3-gallate ...
Oct 21, 2011 |
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Cell survival protein research reveals surprise structure
Researchers from the Walter and Eliza Hall Institute have found a structural surprise in a type of protein that encourages cell survival, raising interesting questions about how the proteins function to influence ...
Oct 14, 2011 |
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Worm 'cell death' discovery could lead to new drugs for deadly parasite
Researchers from the Walter and Eliza Hall Institute have for the first time identified a 'programmed cell death' pathway in parasitic worms that could one day lead to new treatments for one of the world's ...
Sep 28, 2011 |
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Discovery helps explain why chemo causes drop in platelet numbers
Scientists at the Walter and Eliza Hall Institute have identified a way that chemotherapy causes platelet numbers to drop, answering in the process a decade-old question about the formation of platelets, tiny ...
Sep 25, 2011 |
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Gene therapy kills breast cancer stem cells, boosts chemotherapy
Gene therapy delivered directly to a particularly stubborn type of breast cancer cell causes the cells to self-destruct, lowers chance of recurrence and helps increase the effectiveness of some types of chemotherapy, researchers ...
Sep 12, 2011 |
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Researchers find new hope for treatment of chronic leukemia
While testing a new drug designed to treat chronic leukemia, researchers at Cleveland Clinic discovered new markers that could identify which patients would receive maximum benefit from the treatment.
Aug 17, 2011 |
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List of search results for bcl 2
