News tagged with binding pocket
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Search results for binding pocket
Scientists probe form, function of mysterious protein
Like a magician employing sleight of hand, the protein mitoNEET -- a mysterious but important player in diabetes, cancer and aging -- draws the eye with a flurry of movement in one location while the subtle, ...
Jan 27, 2012 |
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Deciphering the mechanism of an ion pump
From an analysis of the sodium-transporting vacuolar ATPases (V-ATPases) of the bacterium Enterococcus hirae, Takeshi Murata of the RIKEN Systems and Structural Biology Center, Yokohama, and colleagues recently ...
Dec 16, 2011 |
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Team pinpoints amino acid variation in immune response gene linked with ulcerative colitis
The association between the inflammatory bowel disease ulcerative colitis and a gene that makes certain cell surface proteins has been pinpointed to a variant amino acid in a crucial binding site that profoundly influences ...
Dec 15, 2011 |
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Study shows how nutrient levels affect enzyme associated with aging process
(Medical Xpress) -- Restricting calorie intake extends life span in many species, and a new study at the School of Medicine helps illuminate how: Low-nutrient conditions activate an enzyme that helps cells complete their ...
Dec 12, 2011 |
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New class of drugs for the reversible inhibition of proteasomes
As the "recycling plant" of the cell, the proteasome regulates vitally important functions. When it is inhibited, the cell chokes on its own waste. Cancer cells, in particular, are very sensitive because they ...
Nov 22, 2011 |
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Crystalizing the foundations of better antihistamines
Researchers in Japan have solved the structure of a complex between the antihistamine drug doxepin and its target receptor histamine H1 receptor (H1R)1. Led by So Iwata of Kyoto University and the RIKEN Systems ...
Nov 21, 2011 |
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Researchers identify structure of circadian clock protein
(PhysOrg.com) -- Feeling jet-lagged? You may need your internal clock reset. New Cornell research has taken a major step toward treating jet lag and other more serious syndromes by advancing our understanding ...
Nov 15, 2011 |
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Molecule serves as a key in some protein interactions
Research led by St. Jude Children's Research Hospital scientists has identified an unexpected mechanism facilitating some protein interactions that are the workhorses of cells and, in the process, identified ...
Nov 04, 2011 |
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Researchers find molecule that prevents Type 1 diabetes in mice
Researchers at the University of Colorado School of Medicine have found a specific molecule that can prevent the development of type 1 diabetes in mice and has a similar effect on human cells from diabetic patients.
Nov 01, 2011 |
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Research involving thyroid hormone lays foundation for more targeted drug development
Research led by St. Jude Children's Research Hospital scientists advances a strategy for taming the side effects and enhancing the therapeutic benefits of steroids and other medications that work by disrupting the activity ...
Oct 21, 2011 |
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List of search results for binding pocket
