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Mirror images united: Simultaneous binding of both enantiomers of a drug to an enzyme

Chemistry / Biochemistry

created Oct 29, 2009 | popularity 5 / 5 (2) | comments 0

(PhysOrg.com) -- In the binding pockets of enzymes their natural binding partners fit exactly. The principle by which many pharmacological agents work also relies on the fact that these substances fit exactly into the pockets ...


Scorpion venom with nanoparticles slows spread of brain cancer

Scorpion venom with nanoparticles slows spread of brain cancer

Nanotechnology / Bio & Medicine

created Apr 16, 2009 | popularity 4.6 / 5 (10) | comments 3

By combining nanoparticles with a scorpion venom compound already being investigated for treating brain cancer, University of Washington researchers found they could cut the spread of cancerous cells by 98 ...


New class of antibiotics may lead to therapy for drug-resistant tuberculosis

Medicine & Health / Diseases

created Oct 16, 2008 | popularity 4.8 / 5 (5) | comments 0

A team of Rutgers University scientists led by Richard H. Ebright and Eddy Arnold has identified a new antibiotic target and a new antibiotic mechanism that may enable the development of broad-spectrum antibacterial agents ...


Key site in iron metabolism aids in diagnosing anemia of chronic disease

Medicine & Health / Research

created Aug 05, 2008 | popularity 4 / 5 (1) | comments 0

University of Utah School of Medicine researchers have developed a new tool that facilitates diagnosis of anemia related to chronic illness, as well as diseases of iron overload. The results of a study detailing the new tool ...





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Important new model shows how proteins find the right DNA sequences

Important new model shows how proteins find the right DNA sequences

Physics / General Physics

created Mar 16, 2009 | popularity 4.1 / 5 (7) | comments 0

(PhysOrg.com) -- Researchers at Uppsala University and Harvard University have collaboratively developed a new theoretical model to explain how proteins can rapidly find specific DNA sequences, even though ...


A sticky solution for identifying effective probiotics

Chemistry / Biochemistry

created Nov 24, 2009 | popularity 5 / 5 (1) | comments 0

Scientists have crystallised a protein that may help gut bacteria bind to the gastrointestinal tract. The protein could be used by probiotic producers to identify strains that are likely to be of real benefit to people.


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Facebook users' vote ending way short of threshold

Technology / Internet

created Apr 23, 2009 | popularity not rated yet | comments 0

(AP) -- Facebook invited the 200 million people who regularly use the site to vote on its governing documents. But it's unclear how much of a difference it will make.


Gene regulation in humans is closer than expected to simple organisms

Medicine & Health / Research

created Aug 29, 2007 | popularity 4.5 / 5 (8) | comments 0

Using a novel method developed to identify reliably functional binding motifs, researchers from the Weizmann Institute of Science in Israel have performed a genome-wide study of functional human transcription factor binding ...


Metabolic insight to illuminate causes of iron imbalance

Medicine & Health / Research

created Aug 05, 2008 | popularity 4.5 / 5 (2) | comments 0

New insight into key players in iron metabolism has yielded a novel tool for distinguishing among root causes of iron overload or deficiency in humans, the researchers report in the August issue of Cell Metabolism, a publ ...


Flexible neck in cell-receptor DC-SIGN targets more pathogens

Chemistry / Biochemistry

created Jul 14, 2009 | popularity 1 / 5 (1) | comments 0

Pathogen recognition is the foundation of the body's immune response and survival against infection. A small cell-receptor protein called DC-SIGN is part of the immune system, and recognizes certain pathogens, including those ...


Gene regulators bind promiscuously, but often do nothing

Biology /

created Feb 12, 2008 | popularity 5 / 5 (1) | comments 0

Biologists are developing ever more sophisticated means to characterize molecular interactions in living systems. But a new study suggests that many of the interactions detected by a widely-used experimental method are functionally ...


Researchers demonstrate novel method for studying the DNA binding of small molecules

Biology /

created Jun 04, 2007 | popularity 5 / 5 (1) | comments 0

Northeastern University professor Mark C. Williams and colleague Ioana Vladescu have discovered a novel method for studying the DNA binding of small molecules with unprecedented accuracy. Their paper, titled “Quantifying ...


Scientists investigate initial molecular mechanism that triggers neuronal firing

Medicine & Health / Research

created Aug 22, 2007 | popularity 5 / 5 (1) | comments 0

Carnegie Mellon University chemists have solved a decade-long molecular mystery that could eventually help scientists develop drug therapies to treat a variety of disorders, including epilepsy and Alzheimer’s disease.


Digital Life: Want to change Facebook's terms of service? Get 50 million people to agree

Technology / Internet

created Mar 12, 2009 | popularity not rated yet | comments 0

Comments on the Web are often immature or wildly misinformed. It was a pleasant surprise, then, to see Facebook members providing reasonable and articulate feedback in the social-networking's site new civic experiment.



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