News tagged with binding site

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Mirror images united: Simultaneous binding of both enantiomers of a drug to an enzyme

Chemistry / Biochemistry

created Oct 29, 2009 | popularity 5 / 5 (2) | comments 0

(PhysOrg.com) -- In the binding pockets of enzymes their natural binding partners fit exactly. The principle by which many pharmacological agents work also relies on the fact that these substances fit exactly into the pockets ...


Scorpion venom with nanoparticles slows spread of brain cancer

Scorpion venom with nanoparticles slows spread of brain cancer

Nanotechnology / Bio & Medicine

created Apr 16, 2009 | popularity 4.6 / 5 (10) | comments 3

By combining nanoparticles with a scorpion venom compound already being investigated for treating brain cancer, University of Washington researchers found they could cut the spread of cancerous cells by 98 ...


New class of antibiotics may lead to therapy for drug-resistant tuberculosis

Medicine & Health / Diseases

created Oct 16, 2008 | popularity 4.8 / 5 (5) | comments 0

A team of Rutgers University scientists led by Richard H. Ebright and Eddy Arnold has identified a new antibiotic target and a new antibiotic mechanism that may enable the development of broad-spectrum antibacterial agents ...


Key site in iron metabolism aids in diagnosing anemia of chronic disease

Medicine & Health / Research

created Aug 05, 2008 | popularity 4 / 5 (1) | comments 0

University of Utah School of Medicine researchers have developed a new tool that facilitates diagnosis of anemia related to chronic illness, as well as diseases of iron overload. The results of a study detailing the new tool ...





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A sticky solution for identifying effective probiotics

Chemistry / Biochemistry

created Nov 24, 2009 | popularity 5 / 5 (1) | comments 0

Scientists have crystallised a protein that may help gut bacteria bind to the gastrointestinal tract. The protein could be used by probiotic producers to identify strains that are likely to be of real benefit to people.


Hackers leak e-mails, stoke climate debate

Technology / Internet

created Nov 21, 2009 | popularity 4.4 / 5 (49) | comments 32

(AP) -- Computer hackers have broken into a server at a well-respected climate change research center in Britain and posted hundreds of private e-mails and documents online - stoking debate over whether some scientists have ...


When It Comes to Drug Delivery, Size Matters

Nanotechnology / Bio & Medicine

created Nov 20, 2009 | popularity 5 / 5 (2) | comments 0

(PhysOrg.com) -- One of the great promises of nanotechnologies lies in its ability to create drug-containing nanoparticles decorated with targeting molecules that recognize and bind to cancer cells, providing drug delivery ...


New findings suggest strategy to help generate HIV-neutralizing antibodies

Medicine & Health / HIV & AIDS

created Nov 19, 2009 | popularity not rated yet | comments 0

New discoveries about anti-HIV antibodies may bring researchers a step closer to creating an effective HIV vaccine, according to a new paper co-authored by scientists at the Vaccine Research Center of the National Institute ...


New research into the mechanisms of gene regulation

New research into the mechanisms of gene regulation

Medicine & Health / Genetics

created Nov 19, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- A team led by Penn State's Ross Hardison, T. Ming Chu Professor of Biochemistry and Molecular Biology, has taken a large step toward unraveling how regulatory proteins control the production ...


Researchers solve structure of NMDA receptor unit that could be drug target for neurological diseases

Chemistry / Biochemistry

created Nov 12, 2009 | popularity not rated yet | comments 0

A team of scientists at Cold Spring Harbor Laboratory reports on Thursday their success in solving the molecular structure of a key portion of a cellular receptor implicated in Alzheimer's, Parkinson's, and other serious ...


Study points to new uses, unexpected side effects of already existing drugs

Study points to new uses, unexpected side effects of already existing drugs

Medicine & Health / Research

created Nov 04, 2009 | popularity 5 / 5 (3) | comments 0

Scientists at the University of North Carolina at Chapel Hill School of Medicine and the University of California, San Francisco have developed and experimentally tested a technique to predict new target diseases ...


Nanostructured Integrated Circuit Detects Type and Severity of Cancer

Nanotechnology / Bio & Medicine

created Nov 03, 2009 | popularity 5 / 5 (3) | comments 0

(PhysOrg.com) -- A team of investigators from the University of Toronto have used nanomaterials to develop an inexpensive microchip sensitive enough to quickly determine the type and severity of a patient's cancer so that ...


Study reveals a 'missing link' in immune response to disease

Study reveals a 'missing link' in immune response to disease (w/ Video)

Chemistry / Biochemistry

created Nov 02, 2009 | popularity 5 / 5 (1) | comments 0

The immune system's T cells have the unique responsibilities of being both jury and executioner. They examine other cells for signs of disease, including cancers or infections, and, if such evidence is found, ...


Scientists are first to observe the global motions of an enzyme copying DNA

Scientists Are First To Observe The Global Motions Of An Enzyme Copyinng DNA

Chemistry / Biochemistry

created Oct 27, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Scientists here have identified how the motions of an enzyme are related to correctly copying genetic instructions, setting the stage for studies that can uncover what happens when DNA copying ...



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