Biochip advances enable next-generation sequencing technologies

Biochips are essentially tiny laboratories designed to function inside living organisms, and they are driving next-generation DNA sequencing technologies. This powerful combination is capable of solving unique and important ...

A chip with blood vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Sweet solutions for detecting disease

Based at the Institute of Chemistry in the Slovak Academy of Sciences, Ján Tkáč's research combines glycomics – the study of sugars in organisms – with biochip sensors based on nanoparticles and nanotubes. The complexity ...

A SMART(er) way to track influenza

In April 2009, the world took notice as reports surfaced of a virus in Mexico that had mutated from pigs and was being passed from human to human. The H1N1 "swine flu," as the virus was named, circulated worldwide, killing ...

Droplet array sheds light on drug-resistant cancer stem cells

Researchers at the Institute of Bioengineering and Nanotechnology (IBN) have developed a miniaturized biochip for investigating the effect of drugs on cancer stem cells (CSCs). Published recently in Nano Today, this new technology ...

Giving research a boost with cheaper biochips

An EPFL invention has drastically reduced the cost of producing biochips, which are used to measure glucose and drug levels in the blood and to detect biomolecules and cellular signals. This development could make it possible ...

Microbial oasis discovered beneath the Atacama Desert

Two metres below the surface of the Atacama Desert there is an 'oasis' of microorganisms. Researchers from the Center of Astrobiology (Spain) and the Catholic University of the North in Chile have found it in hypersaline ...

Biochip measures glucose in saliva, not blood

For the 26 million Americans with diabetes, drawing blood is the most prevalent way to check glucose levels. It is invasive and at least minimally painful. Researchers at Brown University are working on a new sensor that ...

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Biochip

The development of biochips is a major thrust of the rapidly growing biotechnology industry, which encompasses a very diverse range of research efforts including genomics, proteomics, and pharmaceuticals, among other activities. Advances in these areas are giving scientists new methods for unravelling the complex biochemical processes occurring inside cells, with the larger goal of understanding and treating human diseases. At the same time, the semiconductor industry has been steadily perfecting the science of micro-miniaturization. The merging of these two fields in recent years has enabled biotechnologists to begin packing their traditionally bulky sensing tools into smaller and smaller spaces, onto so-called biochips. These chips are essentially miniaturized laboratories that can perform hundreds or thousands of simultaneous biochemical reactions. Biochips enable researchers to quickly screen large numbers of biological analytes for a variety of purposes, from disease diagnosis to detection of bioterrorism agents.

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