'Game changing' Japan stem-cell study questioned

A Japanese research institute Tuesday said it was probing its own study that promised a 'game changer' way to create stem cells, a feat hailed as revolutionary for the fast-developing field.

Regulating hematopoietic differentiation

Blood cells originate from a small pool of hematopoietic stem cells (HSCs) through a complex process of differentiation steps that are tightly regulated at the transcriptional level. Dissecting the mechanisms underlying this ...

The path from stem cell to maturity

Regulation of gene expression is essential to make sure cell maturation occurs as it should. European research is taking an integrated perspective on how selected steps in liver and blood cell differentiation can be modulated.

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