Osteoporosis

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Osteoporosis is a disease of bone that leads to an increased risk of fracture. In osteoporosis the bone mineral density (BMD) is reduced, bone microarchitecture is disrupted, and the amount and variety of non-collagenous proteins in bone is altered. Osteoporosis is defined by the World Health Organization (WHO) in women as a bone mineral density 2.5 standard deviations below peak bone mass (20-year-old healthy female average) as measured by DXA; the term "established osteoporosis" includes the presence of a fragility fracture. Osteoporosis is most common in women after menopause, when it is called postmenopausal osteoporosis, but may also develop in men, and may occur in anyone in the presence of particular hormonal disorders and other chronic diseases or as a result of medications, specifically glucocorticoids, when the disease is called steroid- or glucocorticoid-induced osteoporosis (SIOP or GIOP). Given its influence is the risk of fragility fracture, osteoporosis may significantly affect life expectancy and quality of life.

Osteoporosis can be prevented with lifestyle changes and sometimes medication; in people with osteoporosis, treatment may involve both. Lifestyle change includes preventing falls and exercise; medication includes calcium, vitamin D, bisphosphonates and several others. Fall-prevention advice includes exercise to tone deambulatory muscles, proprioception-improvement exercises; equilibrium therapies may be included. Exercise with its anabolic effect, may at the same time stop or reverse osteoporosis.

For more information about Osteoporosis, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with bone loss


Sticks and stones break bones, but new study may prevent it

Medicine & Health / Research

created Dec 09, 2009 | popularity 4 / 5 (1) | comments 0

The best way to prevent a fracture is to stop bones from reaching the point where they are prone to breaking, but understanding the process of how bones form and mature has been challenging. Now researchers at the University ...


OU Lab 1 of 4 in nation testing new exercise technique

Medicine & Health / Other

created 4 hours ago | popularity not rated yet | comments 0

A year ago, Michael Bemben, professor of health and exercise science in the University of Oklahoma College of Arts and Sciences, was invited to the National Press Club in Washington, D.C., to formally announce the partnership ...





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NICE guidelines ration affordable osteoporosis drugs

Medicine & Health / Diseases

created Dec 11, 2009 | popularity not rated yet | comments 0

Los Angeles, London, New Delhi, Singapore and Washington DC (December 11, 2009) - Low cost osteoporosis drugs are strictly rationed for the under 75s, and UK physicians hampered by restrictive guidelines, according to findings ...


JAK2 inhibitor demonstrates effective, durable control of myelofibrosis

Medicine & Health / Cancer

created Dec 07, 2009 | popularity not rated yet | comments 0

A first-in-its class oral medication provides significant and durable relief for patients with a rare, debilitating and lethal bone marrow disorder called myelofibrosis, researchers at The University of Texas M. D. Anderson ...


Gene therapy and stem cells save limb

Medicine & Health / Research

created Dec 08, 2009 | popularity not rated yet | comments 0

Blood vessel blockage, a common condition in old age or diabetes, leads to low blood flow and results in low oxygen, which can kill cells and tissues. Such blockages can require amputation resulting in loss of limbs. Now, ...


Successful stem cell therapy for treatment of eye disease

Medicine & Health / Research

created Dec 10, 2009 | popularity not rated yet | comments 0

Newly published research, by investigators, at the North East England Stem Cell Institute (NESCI) in the journal Stem Cells reported the first successful treatment of eight patients with "Limbal Stem Cell Deficiency" (LSCD) ...



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