News tagged with brain enzyme
Study reveals enzyme function, could help find muscular dystrophy therapies
Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 ...
Jan 09, 2012 |
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Regulatory enzyme overexpression may protect against neurodegeneration in Huntington's disease
Treatment that increases brain levels of an important regulatory enzyme may slow the loss of brain cells that characterizes Huntington's disease (HD) and other neurodegenerative disorders. In a report receiving advance online ...
Medicine & Health / Neuroscience
Dec 18, 2011 |
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Characterizing a toxic offender
The brains of individuals with Alzheimer's disease contain protein aggregates called plaques and tangles, which interfere with normal communication between nerve cells and cause progressive learning and memory ...
Medicine & Health / Neuroscience
Dec 09, 2011 |
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Poor recycling of BACE1 enzyme could promote Alzheimer's disease
Sluggish recycling of a protein-slicing enzyme could promote Alzheimer's disease, according to a study published online on November 21 in The Journal of Cell Biology.
Nov 21, 2011 |
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Inflammation controlled differently in brain and other tissues, study finds
A team led by scientists from The Scripps Research Institute has identified a new metabolic pathway for controlling brain inflammation, suggesting strategies for treating it.
Oct 20, 2011 |
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To combat deadly brain cancer, target the stem cells
Researchers have uncovered a new target that could stop the growth of glioblastoma, a deadly form of brain cancer. In the July 8th issue of the journal Cell, a Cell Press publication, a new study identifies an enzyme found ...
Jul 07, 2011 |
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New direction for epilepsy treatment
If common anticonvulsant drugs fail to manage epileptic seizures, then perhaps the anti-inflammatory route is the way to go. That's according to Mattia Maroso and colleagues from the Mario Negri Institute for Pharmacological ...
Medicine & Health / Neuroscience
Mar 28, 2011 |
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Virus might fight brain tumors better if armed with bacterial enzyme, study shows
New research shows that oncolytic viruses, which are engineered to destroy cancer cells, might be more effective in treating deadly brain tumors if equipped with an enzyme that helps them penetrate the tumor.
Jan 13, 2011 |
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Loss of epigenetic regulators causes mental retardation (w/ Video)
(PhysOrg.com) -- Developing neurons don’t just need the right genes to guide them as they grow, they need access to the right genes at the right times. The improper functioning of one specific protein complex that normally ...
Medicine & Health / Neuroscience
Jan 11, 2010 |
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Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer
Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene. This breakthrough ...
Nov 22, 2009 |
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Research reveals lipids' unexpected role in triggering death of brain cells
The lipid that accumulates in brain cells of individuals with an inherited enzyme disorder also drives the cell death that is a hallmark of the disease, according to new research led by St. Jude Children's Research Hospital ...
Nov 12, 2009 |
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Experimental treatment halts hypoxic-ischemic brain injury in newborns
Inhibiting an enzyme in the brains of newborns suffering from oxygen and blood flow deprivation stops a type of brain damage that is a leading cause of cerebral palsy, mental retardation and death, according to researchers ...
Medicine & Health / Neuroscience
Jul 29, 2009 |
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Scientists present first genetic evidence for why placebos work
usually mere sugar pills designed to represent "no treatment" in a clinical treatment study. The effectiveness of the actual medication is compared with the placebo to determine if the medication works.
Jul 20, 2009 |
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Protein linked to Alzheimer's disease doesn't act alone
A team of U.S. investigators led by neuroscientists at Georgetown University Medical Center (GUMC) are steadily uncovering the role that amyloid precursor protein (APP) - the protein implicated in development of Alzheimer's ...
Jun 10, 2009 |
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Stunning Finding: Compounds Protect Against Cerebral Palsy
(PhysOrg.com) -- Two compounds developed by Northwestern University chemists have been shown to be effective in pre-clinical trials in protecting against cerebral palsy, a condition caused by neurodegeneration that affects ...
Feb 25, 2009 |
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