News tagged with burnham institute for medical research


Scientists identify human monoclonal antibodies effective against bird and seasonal flu viruses

Biology /

created Feb 22, 2009 | popularity 5 / 5 (7) | comments 1

Researchers at the Dana-Farber Cancer Institute, Burnham Institute for Medical Research and the Centers for Disease Control and Prevention have reported the identification of human monoclonal antibodies (mAb) that neutralize ...


Researchers illuminate mechanisms that regulate DNA damage control and replication

Biology /

created Jan 05, 2009 | popularity 3 / 5 (1) | comments 0

Scientists at Burnham Institute for Medical Research (Burnham) have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA replication and reinitiating ...





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Unraveling how cells respond to low oxygen

Medicine & Health / Research

created Aug 05, 2009 | popularity not rated yet | comments 0

Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. The REDD1 protein is a critical inhibitor of the mTOR signaling pathway, ...


When proteins change partners

Chemistry / Biochemistry

created Sep 11, 2009 | popularity not rated yet | comments 0

Dieter Wolf, M.D., and colleagues at Burnham Institute for Medical Research (Burnham) have illuminated how competition between proteins enhances combinatorial diversity during ubiquitination (the process that marks proteins ...


Stem cell research uncovers mechanism for type 2 diabetes

Medicine & Health / Diseases

created Feb 12, 2009 | popularity 5 / 5 (2) | comments 0

Taking clues from their stem cell research, investigators at the University of California San Diego (UC San Diego) and Burnham Institute for Medical Research (Burnham) have discovered that a signaling pathway involved in ...


MicroRNAs help control HIV life cycle

Chemistry / Biochemistry

created Jun 25, 2009 | popularity 4 / 5 (1) | comments 0

Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells. In particular, ...


The path to new antibiotics: Researchers find vulnerable enzyme in pathogens

Chemistry / Biochemistry

created Aug 27, 2009 | popularity not rated yet | comments 0

Researchers at Burnham Institute for Medical Research (Burnham), University of Texas Southwestern Medical Center and University of Maryland have demonstrated that an enzyme that is essential to many bacteria can be targeted ...


Scientists develop method for comprehensive proteome analysis

Biology / Cell & Microbiology

created Apr 08, 2009 | popularity 5 / 5 (2) | comments 0

Investigators at Burnham Institute for Medical Research (Burnham) have deciphered a large percentage of the total protein complement (proteome) in Schizosaccharomyces pombe (S. pombe) fission yeast.


Creating ideal neural cells for clinical use

Medicine & Health / Research

created Apr 13, 2009 | popularity not rated yet | comments 0

Investigators at the Burnham Institute for Medical Research (Burnham) have developed a protocol to rapidly differentiate human embryonic stem cells (hESCs) into neural progenitor cells that may be ideal for transplantation. ...


New insights into limb formation

Medicine & Health / Research

created Aug 12, 2009 | popularity 3 / 5 (1) | comments 0

Investigators at Burnham Institute for Medical Research (Burnham) and the University of Connecticut Health Center (U.C.H.C.) have gained new understanding of the role hyaluronic acid (HA) plays in skeletal growth, chondrocyte ...


Researchers discover 'on switch' for cell death signaling mechanism

Biology /

created Jan 05, 2009 | popularity 4.5 / 5 (6) | comments 0

Scientists at Burnham Institute for Medical Research (Burnham) have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for ...


Carbohydrate acts as tumor suppressor

Medicine & Health / Cancer

created Jul 06, 2009 | popularity 5 / 5 (3) | comments 1

Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specialized complex sugar molecules (glycans) that anchor cells into place act as tumor suppressors in breast and prostate cancers. These ...



List of search results for burnham institute for medical research