News tagged with cancer genomes
Drugs targeting chromosomal instability may fight a particular breast cancer subtype
Another layer in breast cancer genetics has been peeled back. A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of ...
Feb 06, 2012 |
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Cancer drugs shown to cause mutations in mice offspring
(Medical Xpress) -- For many years, most of the studies done to see what effects cancer treatment has on the offspring of survivors, has involved radiation. This is because radiation is known to cause mutations in cells. ...
Jan 31, 2012 |
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Inherited risk factors for childhood leukemia are more common in Hispanic patients
Hispanic children are more likely than those from other racial and ethnic backgrounds to be diagnosed with acute lymphoblastic leukemia (ALL) and are more likely to die of their disease. Work led by St. Jude Children's Research ...
Jan 30, 2012 |
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Patterns of chromosome abnormality: The key to cancer?
A healthy genome is characterized by 23 pairs of chromosomes, and even a small change in this structure — such as an extra copy of a single chromosome — can lead to severe physical impairment. So it's no surprise ...
Jan 23, 2012 |
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Gender differences in liver cancer risk explained by small changes in genome
Men are four times more likely to develop liver cancer compared to women, a difference attributed to the sex hormones androgen and estrogen. Although this gender difference has been known for a long time, ...
Jan 19, 2012 |
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Rigged to explode? Inherited mutation links exploding chromosomes to cancer
An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive types of cancer, scientists at the European Molecular Biology ...
Jan 19, 2012 |
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New method pinpoints important gene-regulation proteins
A novel technique has been developed and demonstrated at Penn State University to map the proteins that read and regulate chromosomes -- the string-like structures inside cells that carry genes. The specific ...
Jan 18, 2012 |
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St. Jude Children's Research Hospital launches data website for genome project
St. Jude Children's Research Hospital has launched a freely available website for published research results from the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project (PCGP). ...
Jan 11, 2012 |
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Cancer sequencing project identifies potential approaches to combat aggressive leukemia
Researchers have discovered that a subtype of leukemia characterized by a poor prognosis is fueled by mutations in pathways distinctly different from a seemingly similar leukemia associated with a much better outcome. The ...
Jan 11, 2012 |
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Scientists create first 3-D map of human genome
(PhysOrg.com) -- For the first time, scientists have developed a method for generating accurate three-dimensional models of the entire DNA strand of a cell, known as a genome.
Jan 04, 2012 |
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Genetic predisposition to disease common in two supercentenarians: study
The first-ever published whole-genome sequences of not just one, but two supercentenarians, aged more than 114 years, reveal that both unusual and common genetic phenomena contribute to the genetic background of extreme human ...
Jan 03, 2012 |
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Gene identified in increasing pancreatic cancer risk
Mutations in the ATM gene may increase the hereditary risk for pancreatic cancer, according to data published in Cancer Discovery, the newest journal of the American Association for Cancer Research.
Dec 29, 2011 |
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Cleveland Clinic researcher discovers genetic cause of thyroid cancer
Cleveland Clinic researchers have discovered three genes that increase the risk of thyroid cancer, which is has the largest incidence increase in cancers among both men and women.
Dec 23, 2011 |
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Gene fusion in lung cancer afflicting never-smokers may be target for therapy
Smoking is a well-known risk factor for lung cancer, but nearly 25% of all lung cancer patients have never smoked. In a study published online today in Genome Research, researchers have identified a previously unknown gene f ...
Dec 22, 2011 |
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Single gene links rare and unrelated cancers
Scientists at the BC Cancer Agency, Vancouver Coastal Health Research Institute, and the University of British Columbia are excited over a discovery made while studying rare tumour types.
Dec 21, 2011 |
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