Cancer vaccine

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The term cancer vaccine refers to a vaccine that either prevents infections with cancer-causing viruses, treats existing cancer or prevents the development of cancer in certain high risk individuals.

Some cancers, such as cervical cancer and some liver cancers, are caused by viruses, and traditional vaccines against those viruses, such as HPV vaccine and Hepatitis B vaccine, will prevent those cancers.

Scientists have also been trying to develop vaccines against existing cancers. Some researchers believe that cancer cells routinely arise and are destroyed by the healthy immune system; cancer forms when the immune system fails to destroy them. One approach to cancer vaccination is to separate proteins from cancer cells and immunize cancer patients against those proteins, in the hope of stimulating an immune reaction that would kill the cancer cells. Therapeutic cancer vaccines are being developed for the treatment of breast, lung, colon, skin, kidney, prostate, and other cancers..

On April 14 2009 Dendreon Corporation announced that their Phase III clinical trial of Provenge, a cancer vaccine designed to treat prostate cancer, had succeeded in demonstrating an increase in survival. This is the first robust, statistically significant Phase III result for a cancer vaccine, although the data have yet to be scrutinized by the U.S. Food and Drug Administration or by European Union regulatory agencies. Dendreon is forecasting marketing approval by the FDA by 2010

If Provenge is approved by the FDA, Dendreon will have opened a new era in cancer care.[citation needed]

For more information about Cancer vaccine, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with cancer vaccine

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Implant-based cancer vaccine is first to eliminate tumors in mice

Implant-based cancer vaccine is first to eliminate tumors in mice

Medicine & Health / Cancer

created Nov 25, 2009 | popularity 4.7 / 5 (22) | comments 7

(PhysOrg.com) -- A cancer vaccine carried into the body on a carefully engineered, fingernail-sized implant is the first to successfully eliminate tumors in mammals, scientists report this week in the journal ...


HPV vaccine makes girls more cautious about sex

HPV vaccine makes girls more cautious about sex

Medicine & Health / Cancer

created Oct 27, 2009 | popularity 2.5 / 5 (4) | comments 0

(PhysOrg.com) -- Nearly 80% of girls say that having the HPV vaccine makes them think twice about the risks of having sex, according to a University of Manchester study published in the British Journal of ...


Stem cells which 'fool immune system' may provide vaccination for cancer

Medicine & Health / Cancer

created Oct 08, 2009 | popularity 4.5 / 5 (2) | comments 0

Scientists from the United States and China have revealed the potential for human stem cells to provide a vaccination against colon cancer, reports a study published in Stem Cells.


Prostate Tumors Can Change the Function of Immune Cells in Mice

Medicine & Health / Cancer

created Oct 07, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Researchers have discovered that prostate tumors in mice can cause immune cells known as CD8+ T cells to change their function from cells that have antitumor activity to cells that suppress immune responses. ...


Study finds promise in combined transplant/vaccine therapy for high-risk leukemia

Study finds promise in combined transplant/vaccine therapy for high-risk leukemia

Medicine & Health / Cancer

created Aug 24, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Two of the most powerful approaches to cancer treatment -- a stem cell transplant and an immune system-stimulating vaccine -- appear to reinforce each other in patients with an aggressive, ...


Cornell makes cancer vaccine for clinical use

Medicine & Health / Cancer

created Aug 20, 2009 | popularity 5 / 5 (2) | comments 0

The Bioproduction Facility at Cornell University has produced the first batch of NY-ESO-1 recombinant protein—a cancer vaccine—that will be used in clinical trials for patients facing either ovarian cancer or melanoma. The ...


Could therapeutic vaccines treat hard to beat breast cancers?

Medicine & Health / Cancer

created Jul 27, 2009 | popularity 1 / 5 (1) | comments 0

A comprehensive analysis of nearly 1,600 tumor samples has found that CT-X genes are expressed in nearly half the breast cancers that lack the estrogen receptor (ER). CT-X gene products are the targets of therapeutic cancer ...


One step closer to turning off cancer genes with gene-silencing

One step closer to turning off cancer genes with gene-silencing

Medicine & Health / Cancer

created Jun 04, 2009 | popularity 5 / 5 (3) | comments 0

(PhysOrg.com) -- Researchers at The University of Queensland have developed a way to deliver drugs which can specifically shut down cancer-causing genes in tumour cells while sparing normal healthy tissues.


Immune therapies finally working against cancer (AP)

Immune therapies finally working against cancer

Medicine & Health / Cancer

created May 31, 2009 | popularity 5 / 5 (7) | comments 2

(AP) -- First there was surgery, then chemotherapy and radiation. Now, doctors have overcome 30 years of false starts and found success with a fourth way to fight cancer: using the body's natural defender, ...


Antibody gives cancer the recognition it deserves

Medicine & Health / Cancer

created Apr 22, 2009 | popularity 5 / 5 (1) | comments 0

In concept, the human immune system has the power to destroy cancer cells with great specificity. Therefore, cancer vaccines, like vaccines against influenza or other diseases, offer the hope of enticing the immune system ...


Company says prostate cancer vaccine shows promise

Medicine & Health / Medications

created Apr 14, 2009 | popularity 5 / 5 (3) | comments 0

(AP) -- The maker of an experimental treatment for prostate cancer says the vaccine has met a key goal in a late-stage study.


Research defines dendritic cell lineage

Medicine & Health / Research

created Mar 19, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Dendritic cells were discovered more than 30 years ago, but their pedigree has never been fully charted. They were known to be key immune system cells born in bone marrow, but their adolescence remained a ...


Cervical cancer prevention should focus on vaccinating adolescent girls

Medicine & Health / Health

created Aug 21, 2008 | popularity 5 / 5 (1) | comments 0

The cost-effectiveness of vaccination in the United States against human papillomavirus (HPV), a sexually-transmitted virus that causes cervical cancer, will be optimized by achieving universal vaccine coverage in young adolescent ...