News tagged with capecitabine
Capecitabine
Capecitabine (INN) ( /keɪpˈsaɪtəbiːn/) (Xeloda, Roche) is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.[citation needed] The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil.[citation needed]
For more information about Capecitabine, read the full article at
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Chemo plus radiation before surgery increases tumor response for rectal cancer
Rectal cancer patients who use a new combination of the chemotherapy, Capecitabine, together with five weeks of radiation (50 Gy) before surgery have an 88 percent chance of surviving the cancer three years after treatment, ...
Sep 26, 2011 |
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Sorafenib significantly improves the length of time before breast cancer worsens
Berlin, Germany: One of the first of a series of trials to investigate the use of sorafenib - a targeted anti-cancer drug - for the treatment of advanced breast cancer has found that if it is combined with the chemotherapy ...
Sep 23, 2009 |
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Triple drug combination is promising option to treat metastatic HER2+ breast cancer
Combining two chemotherapy drugs with trastuzumab (Herceptin) to treat women who have metastatic HER2+ breast cancer may offer physicians another choice in their treatment options.
May 15, 2009 |
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Search results for capecitabine
Importance of echocardiography to evaluate cardio toxicity in cancer patients
One study presented at the meeting, which is being held in Budapest, Hungary, 7 to 10 December, reports on an initiative using echocardiography to document early warning signs of adverse effects from trastuzumab (Herceptin)¹, ...
Medicine & Health / Cardiology
Dec 07, 2011 |
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Clinical trial shows benefit to adding avastin to neoadjuvant chemotherapy in breast cancer patients
Amid the controversy surrounding the Food and Drug Administration's ruling that Avastin should no longer be used to treat metastatic breast cancer, a new multinational Phase III clinical trial shows that Avastin significantly ...
Aug 23, 2011 |
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Researchers link genetic marker to rectal cancer treatment
A team of researchers led by Keck School of Medicine of the University of Southern California (USC) oncologist Heinz-Josef Lenz, M.D., has identified a genetic marker that may predict which patients with rectal cancer can ...
Jul 06, 2011 |
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Many patients with advanced cancers get treatments that won't help
A study of more than 1,000 patients with colon cancer that had spread to distant sites found that one in eight was treated with at least one drug regimen that was not recommended. Those patients were exposed to significant ...
Jun 07, 2011 |
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GOLFIG increased progression-free survival in colorectal cancer patients
Oncologists can use colorectal cancer patients' own immune system to boost the effects of chemotherapy and increase progression-free survival, according to Phase III study results presented at the AACR 102nd Annual Meeting ...
Apr 06, 2011 |
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Effects of chemoradiation therapy by using capecitabine on gastric cancer patients
A research team from Singapore reviewed the outcome of patients with resected gastric cancers treated with capecitabine and radiation compared to 5-fluorouracil with radiation or fluoropyrimidine-based chemotherapy only. ...
Sep 20, 2010 |
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Addition of trastuzumab to chemotherapy for stomach cancer extends survival by nearly 3 months
An Article published Online First by The Lancet says that for patients with HER2-positive advanced gastric cancer, addition of tastuzumab to standard cisplatinum/fluoropyrimidine chemotherapy results in a median survival of 13. ...
Aug 19, 2010 |
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Study shows use of Herceptin in treatment of stomach cancer prolongs life
(PhysOrg.com) -- A study involving a University of Glasgow cancer specialist has found that using Herceptin increases survival rates among those with stomach cancer.
Sep 25, 2009 |
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Lapatinib shows minimal effect against liver cancer
Use of the molecularly targeted agent lapatinib to delay tumor growth and improve the survival of patients with inoperable hepatocellular carcinoma, or liver cancer, only benefited certain subgroups of patients. While results ...
Sep 08, 2009 |
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Study reveals new genetic culprit in deadly skin cancer
Drawing on the power of DNA sequencing, National Institutes of Health researchers have identified a new group of genetic mutations involved in the deadliest form of skin cancer, melanoma. This discovery is particularly encouraging ...
Aug 31, 2009 |
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List of search results for capecitabine
