News tagged with cd8 t cells
Scientists discover way to amp up power of killer T cells
Researchers with UCLA's Jonsson Comprehensive Cancer Center have discovered a way to amp up the power of killer T-cells, called CD8 cells, making them more functional for longer periods of time and boosting their ability ...
May 10, 2011 |
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Trial suggests statin may affect markers associated with progression of HIV
A recent multicenter clinical trial of atorvastatin, a type of cholesterol-lowering drug, found that although the drug did not inhibit plasma HIV RNA levels, it did inhibit expression of cellular markers of immune activation ...
Medicine & Health / HIV & AIDS
Feb 16, 2011 |
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Study reveals a genetic signature of autoimmune disease
(PhysOrg.com) -- Researchers have identified a cellular genetic signature that predicts prognosis in two different autoimmune diseases. It is hoped the findings could one day help to guide therapy and might ...
Apr 20, 2010 |
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New TB booster shows promise
A booster shot appears to improve tuberculosis (TB) resistance in previously vaccinated adults, according to new research in South Africa.
Mar 16, 2010 |
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Circulating Mesothelin Serves as a Marker of Pancreatic Cancer
(PhysOrg.com) -- Researchers have expanded on previous studies, and there may be a new weapon in the arsenal for immune-based strategies in treating pancreatic cancer - mesothelin protein. Findings also showed that circulating ...
Oct 22, 2009 |
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The difficult Way to HIV Vaccine
T cells are key players in the immune response to HIV, which are able to delete infected cells. This capacity is used for vaccine development against HIV. “To date however, success of this strategy remains elusive. Our understanding ...
Medicine & Health / HIV & AIDS
Sep 16, 2009 |
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Scientists find key to strengthening immune response to chronic infection
A team of researchers from The Wistar Institute has identified a protein that could serve as a target for reprogramming immune system cells exhausted by exposure to chronic viral infection into more effective "soldiers" against ...
Aug 06, 2009 |
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Transplant drug stimulates immune memory
Rapamycin, a drug given to transplant recipients to suppress their immune systems, has a paradoxical effect on cells responsible for immune memory, scientists at the Emory Vaccine Center have discovered.
Jun 21, 2009 |
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Chronic infection now clearly tied to immune-system protein (w/Video)
A new study finds the cross-talk between 'killer T-cells' and 'helper T-cells' can only happen in the presence of interleukin-21, a powerful immune-system protein. UAB researchers say if interleukin-21 is missing, the immune ...
May 14, 2009 |
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Scientists identify how key protein keeps chronic infection in check
Why is the immune system able to fight off some viruses but not others, leading to chronic, life-threatening infections like HIV and hepatitis C?
May 08, 2009 |
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Brain structure assists in immune response (Video)
For the first time, a team of researchers at the University of Pennsylvania School of Veterinary Medicine have imaged in real time the body's immune response to a parasitic infection in the brain.
Biology /
Jan 28, 2009 |
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Cytotoxic T cell
A cytotoxic T cell (also known as TC, CTL, T-Killer cell, cytolytic T cell, CD8+ T-cells or killer T cell) belongs to a sub-group of T lymphocytes (a type of white blood cell) that are capable of inducing the death of infected somatic or tumor cells; they kill cells that are infected with viruses (or other pathogens), or are otherwise damaged or dysfunctional. Most cytotoxic T cells express T-cell receptors (TCRs) that can recognize a specific antigenic peptide bound to Class I MHC molecules, present on all nucleated cells, and a glycoprotein called CD8, which is attracted to non-variable portions of the Class I MHC molecule. The affinity between CD8 and the MHC molecule keeps the TC cell and the target cell bound closely together during antigen-specific activation. CD8+ T cells are recognized as TC cells once they become activated and are generally classified as having a pre-defined cytotoxic role within the immune system.
For more information about Cytotoxic T cell, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
