Programmed cell death

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Programmed cell-death (or PCD) is death of a cell in any form, mediated by an intracellular program. In contrast to necrosis, which is a form of cell-death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process which generally confers advantage during an organism's life-cycle. PCD serves fundamental functions during both plant and metazoa (multicellular animals) tissue development.

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News tagged with cell death

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Protein could prevent blocked arteries

Protein could prevent blocked arteries

Medicine & Health / Research

created Dec 09, 2008 | popularity 4.6 / 5 (28) | comments 0

(PhysOrg.com) -- For the first time, researchers have found that a modified form of a naturally occurring protein, N-cadherin, could prevent blocked arteries. Blocked arteries are a major cause of heart attacks ...


Nanoparticles used in common household items caused genetic damage in mice

Nanotechnology / Bio & Medicine

created Nov 16, 2009 | popularity 4.8 / 5 (24) | comments 11

Titanium dioxide (TiO2) nanoparticles, found in everything from cosmetics to sunscreen to paint to vitamins, caused systemic genetic damage in mice, according to a comprehensive study conducted by researchers at UCLA's Jonsson ...


Cutting calories could limit muscle wasting in later years

Medicine & Health / Health

created Sep 16, 2008 | popularity 4.7 / 5 (21) | comments 0

Chemical concoctions can smooth over wrinkles and hide those pesky grays, but what about the signs of aging that aren't so easy to fix, such as losing muscle mass? Cutting calories early could help, say University of Florida ...


Potential to prevent loss of insulin in type 2 diabetes

Medicine & Health / Diseases

created Jul 14, 2008 | popularity 4.6 / 5 (17) | comments 0

There are two completely different diseases known as diabetes. Type 1 is an autoimmune condition that often starts in childhood or adolescence. Type 2 is a metabolic disorder sometimes associated with lifestyle. In both cases, ...


By amplifying cell death signals, scientists make precancerous cells self-destruct

Medicine & Health / Research

created Aug 15, 2008 | popularity 4.6 / 5 (17) | comments 0

When a cell begins to multiply in a dangerously abnormal way, a series of death signals trigger it to self-destruct before it turns cancerous. Now, in research to appear in the August 15 issue of Genes & Development, Rockef ...


Newly Discovered Fat Molecule: An Undersea Killer with an Upside

Newly Discovered Fat Molecule: An Undersea Killer with an Upside

Chemistry / Biochemistry

created Nov 05, 2009 | popularity 4.8 / 5 (10) | comments 0

(PhysOrg.com) -- A chemical culprit responsible for the rapid, mysterious death of phytoplankton in the North Atlantic Ocean has been found by collaborating scientists at Rutgers University and the Woods Hole ...


New way to kill cancer found using body's immune system

Medicine & Health / Cancer

created Jul 21, 2009 | popularity 5 / 5 (9) | comments 6

(PhysOrg.com) -- Scientists have discovered a new way of killing cancer cells in a breakthrough that could eventually lead to new treatments for a range of different cancers.


An Achilles heel in cancer cells

Medicine & Health / Cancer

created Dec 08, 2008 | popularity 4.4 / 5 (7) | comments 0

A protein that shields tumor cells from cell death and exerts resistance to chemotherapy has an Achilles heel, a vulnerability that can be exploited to target and kill the very tumor cells it usually protects, researchers ...


Memories of the way they used to be

Memories of the way they used to be

Biology / Biotechnology

created Sep 18, 2009 | popularity 4.3 / 5 (7) | comments 2

A team of researchers from the University of California, San Diego School of Medicine and the Salk Institute for Biological Studies in La Jolla have developed a safe strategy for reprogramming cells to a pluripotent ...


Researchers discover 'on switch' for cell death signaling mechanism

Biology /

created Jan 05, 2009 | popularity 4.5 / 5 (6) | comments 0

Scientists at Burnham Institute for Medical Research (Burnham) have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for ...


Alzheimer’s Findings Resolve Dispute Over How Disease Kills Brain Cells

Medicine & Health / Neuroscience

created Apr 15, 2009 | popularity 4.2 / 5 (6) | comments 0

(PhysOrg.com) -- For a decade, Alzheimer's disease researchers have been entrenched in debate about one of the mechanisms believed to be responsible for brain cell death and memory loss in the illness.


Researchers turn cancer friend into cancer foe

Medicine & Health / Cancer

created Oct 07, 2008 | popularity 4 / 5 (6) | comments 0

Burnham Institute for Medical Research today announced that scientists have created a peptide that binds to Bcl-2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer. ...


Shared survival mechanism explains why 'good' nerve cells last and 'bad' cancer cells flourish

Biology /

created Dec 15, 2008 | popularity 4.6 / 5 (5) | comments 0

Cancer cells and nervous system neurons may not look or act alike, but both use strikingly similar ways to survive, according to new research from the University of North Carolina at Chapel Hill School of Medicine.


New target discovered to treat epileptic seizures following brain trauma or stroke

Medicine & Health / Research

created Dec 05, 2008 | popularity 4.4 / 5 (5) | comments 0

New therapies for some forms of epilepsy may soon be possible, thanks to a discovery made by a team of University of British Columbia and Vancouver Coastal Health Research Institute neuroscience researchers.


Reseachers foil seasonal programmed brain cell death in living birds

Seasonal programmed brain cell death foiled in living birds

Biology /

created Jul 09, 2008 | popularity 5 / 5 (4) | comments 0

Neurons in brains of one songbird species equipped with a built-in suicide program that kicks in at the end of the breeding season have been kept alive for seven days in live birds by researchers trying to ...