Programmed cell death

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Programmed cell-death (or PCD) is death of a cell in any form, mediated by an intracellular program. In contrast to necrosis, which is a form of cell-death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process which generally confers advantage during an organism's life-cycle. PCD serves fundamental functions during both plant and metazoa (multicellular animals) tissue development.

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News tagged with cell death

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Nanoparticles used in common household items caused genetic damage in mice

Nanotechnology / Bio & Medicine

created Nov 16, 2009 | popularity 4.8 / 5 (24) | comments 11

Titanium dioxide (TiO2) nanoparticles, found in everything from cosmetics to sunscreen to paint to vitamins, caused systemic genetic damage in mice, according to a comprehensive study conducted by researchers at UCLA's Jonsson ...


Newly Discovered Fat Molecule: An Undersea Killer with an Upside

Newly Discovered Fat Molecule: An Undersea Killer with an Upside

Chemistry / Biochemistry

created Nov 05, 2009 | popularity 4.8 / 5 (10) | comments 0

(PhysOrg.com) -- A chemical culprit responsible for the rapid, mysterious death of phytoplankton in the North Atlantic Ocean has been found by collaborating scientists at Rutgers University and the Woods Hole ...


New way to kill cancer found using body's immune system

Medicine & Health / Cancer

created Jul 21, 2009 | popularity 5 / 5 (9) | comments 6

(PhysOrg.com) -- Scientists have discovered a new way of killing cancer cells in a breakthrough that could eventually lead to new treatments for a range of different cancers.


Alzheimer’s Findings Resolve Dispute Over How Disease Kills Brain Cells

Medicine & Health / Neuroscience

created Apr 15, 2009 | popularity 4.2 / 5 (6) | comments 0

(PhysOrg.com) -- For a decade, Alzheimer's disease researchers have been entrenched in debate about one of the mechanisms believed to be responsible for brain cell death and memory loss in the illness.


A sticky business -- how cancer cells become more 'gloopy' as they die

Chemistry / Biochemistry

created Mar 15, 2009 | popularity 5 / 5 (1) | comments 1

The viscosity, or 'gloopiness', of different parts of cancer cells increases dramatically when they are blasted with light-activated cancer drugs, according to new images that provide fundamental insights into how cancer ...


New understanding about mechanism for cell death after stroke leads to possible therapy

Medicine & Health / Research

created Nov 22, 2009 | popularity not rated yet | comments 0

Scientists at the Brain Research Centre, a partnership of the University of British Columbia Faculty of Medicine and Vancouver Coastal Health Research Institute, have uncovered new information about the mechanism by which ...


Now hear this: Mouse study sheds light on hearing loss in older adults

Medicine & Health / Genetics

created Nov 09, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- Becoming "hard of hearing" is a standard but unfortunate part of aging: A syndrome called age-related hearing loss affects about 40 percent of people over 65 in the United States, and will afflict an estimated ...


Too much of a good thing? Scientists explain cellular effects of vitamin A overdose and deficiency

Medicine & Health / Research

created Oct 08, 2009 | popularity 4 / 5 (4) | comments 0

If a little vitamin A is good, more must be better, right? Wrong! New research published online in the FASEB Journal shows that vitamin A plays a crucial role in energy production within cells, explaining why too much or too ...


Research puts a 'Fas' to the cause of programmed cell death

Research puts a 'Fas' to the cause of programmed cell death

Medicine & Health / Research

created Sep 30, 2009 | popularity 4.7 / 5 (3) | comments 0

Walter and Eliza Hall Institute researchers have put an end to a 10-year debate over which form of a molecular messenger called Fas ligand is responsible for killing cells during programmed cell death (also ...


How proteins talk to each other: Caspase-3 cleaves in unforeseen ways

Biology / Cell & Microbiology

created Sep 21, 2009 | popularity not rated yet | comments 0

Investigators at Burnham Institute for Medical Research have identified novel cleavage sites for the enzyme caspase-3 (an enzyme that proteolytically cleaves target proteins). Using an advanced proteomic technique called ...


Memories of the way they used to be

Memories of the way they used to be

Biology / Biotechnology

created Sep 18, 2009 | popularity 4.3 / 5 (7) | comments 2

A team of researchers from the University of California, San Diego School of Medicine and the Salk Institute for Biological Studies in La Jolla have developed a safe strategy for reprogramming cells to a pluripotent ...


Important development in the treatment of MS

Important development in the treatment of multiple sclerosis reported

Medicine & Health / Research

created Aug 24, 2009 | popularity 5 / 5 (2) | comments 1

A major step forward, with important implications for understanding how to reduce the severity of multiple sclerosis, has been made by scientists at the University of Bristol. The results are published online ...


Hepatitis C virus channels efforts into cell survival

Medicine & Health / Research

created Aug 17, 2009 | popularity not rated yet | comments 0

Researchers at the University of Leeds have discovered a previously unknown mechanism that allows the hepatitis C virus (HCV) to remain in the body for decades.


Study supports DNA repair-blocker research in cancer therapy

Medicine & Health / Cancer

created Aug 17, 2009 | popularity 4 / 5 (1) | comments 0

Scientists at Dana-Farber Cancer Institute have uncovered the mechanism behind a promising new approach to cancer treatment: damaging cancer cells' DNA with potent drugs while simultaneously preventing the cells from repairing ...


Novel cancer gene accelerates or stops tumour growth

Medicine & Health / Cancer

created May 27, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Researchers at the Hospital for Sick Children (SickKids) and the University of Toronto have found a gene that plays a crucial role in the development of rhabdomyosarcoma - the most common childhood sarcoma ...