News tagged with cell signaling
Crosstalk between critical cell-signaling pathways holds clues to tumor invasion and metastasis
Nov 25, 2009 |
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Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers ...
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Arsenic biomethylation required for oxidative DNA damage
Nov 23, 2009 |
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Biomethylation of arsenic compounds appears to cause oxidative DNA damage and to increase their carcinogenicity, according to a new study published online November 23 in the Journal of the National Cancer Institute.
Tissue tension regulates tumor progression
Nov 23, 2009 |
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(PhysOrg.com) -- UCSF scientists have shown for the first time that the rigidity of a tissue can induce cancer. The research team identified an enzyme that is crucial for regulating tissue stiffness and demonstrated that ...
Computational microscope peers into the working ribosome (w/ Video)
Nov 23, 2009 |
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Two new studies reveal in unprecedented detail how the ribosome interacts with other molecules to assemble new proteins and guide them toward their destination in biological cells. The studies used molecular ...
Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer
Nov 22, 2009 |
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Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene. This breakthrough ...
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