News tagged with cells nucleus
Discovery of extremely long-lived proteins may provide insight into cell aging
One of the big mysteries in biology is why cells age. Now scientists at the Salk Institute for Biological Studies report that they have discovered a weakness in a component of brain cells that may explain ...
Feb 03, 2012 |
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New RNA-based therapeutic strategies for controlling gene expression
Small RNA-based nucleic acid drugs represent a promising new class of therapeutic agents for silencing abnormal or overactive disease-causing genes, and researchers have discovered new mechanisms by which ...
Feb 02, 2012 |
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SUMO-snipping protein plays crucial role in T and B cell development
When SUMO grips STAT5, a protein that activates genes, it blocks the healthy embryonic development of immune B cells and T cells unless its nemesis breaks the hold, a research team led by scientists at The University of Texas ...
Jan 27, 2012 |
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How protein networks stabilize muscle fibers: Same mechanism as for DNA
The same mechanism that stabilises the DNA in the cell nucleus is also important for the structure and function of vertebrate muscle cells. This has been established by RUB-researchers led by Prof. Dr. Wolfgang Linke (Institute ...
Jan 23, 2012 |
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Overcoming cancer drug resistance with nanoparticles
One of the ways in which cancer cells evade anticancer therapy is by producing a protein that pumps drugs out of the cell before these compounds can exert their cell-killing effects. A research team at Northwestern University ...
Nanotechnology / Bio & Medicine
Jan 20, 2012 |
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How the brain puts the brakes on the negative impact of cocaine
Research published by Cell Press in the January 12 issue of the journal Neuron provides fascinating insight into a newly discovered brain mechanism that limits the rewarding impact of cocaine. The study describes protective delaye ...
Medicine & Health / Neuroscience
Jan 11, 2012 |
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Tracking genes' remote controls
As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell's nucleus, genetic sequences known as enhancers act like remote controls, ...
Jan 09, 2012 |
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Brain strain: Christmas shopping when money tight
(AP) -- Chennel King, a nurse from Norwalk, Conn., went Christmas shopping the other day with a new holiday companion: a budget.
Medicine & Health / Psychology & Psychiatry
Dec 18, 2011 |
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Plant seeds protect their genetic material against dehydration
Plant seeds represent a special biological system: They remain in a dormant state with a significantly reduced metabolism and are thus able to withstand harsh environmental conditions for extended periods. ...
Dec 02, 2011 |
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Researchers engineer blood stem cells to fight melanoma
Researchers from UCLA's cancer and stem cell centers have demonstrated for the first time that blood stem cells can be engineered to create cancer-killing T-cells that seek out and attack a human melanoma. The researchers ...
Nov 28, 2011 |
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Surprise role of nuclear structure protein in development
Scientists have long held theories about the importance of proteins called B-type lamins in the process of embryonic stem cells replicating and differentiating into different varieties of cells. New research from a team led ...
Nov 24, 2011 |
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Non-coding RNA relocates genes when it's time to go to work
Cells develop and thrive by turning genes on and off as needed in a precise pattern, a process known as regulated gene transcription. In a paper published in the Nov. 9 issue of the Journal of Neuroscience, researchers at the ...
Medicine & Health / Neuroscience
Nov 10, 2011 |
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Growing without cell division
An international team of scientists, including biologists from the University of North Carolina at Chapel Hill, may have pinpointed for the first time the mechanism responsible for cell polyploidy, a state ...
Nov 01, 2011 |
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How major signaling pathways are wired to our genome gives new insight into disease processes
Whitehead Institute scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. In this way, signaling pathways are targeted to genes that are most relevant to each ...
Oct 27, 2011 |
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Protein that fuels lethal breast cancer growth emerges as potential new drug target
A protein in the nucleus of breast cancer cells that plays a role in fueling the growth of aggressive tumors may be a good target for new drugs, reports a research team at the Duke Cancer Institute.
Oct 17, 2011 |
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