News tagged with cellular function
Researchers restore some function to cells from cystic fibrosis patients
Dec 06, 2009 |
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In an encouraging new development, a team led by Scripps Research Institute scientists has restored partial function to lung cells collected from patients with cystic fibrosis. While there is still much work to be done before ...
Study reveals why certain drug combinations backfire
Nov 13, 2009 |
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Combination drug therapy has become a staple for treating many infections. For instance, doctors treat extensively drug resistant forms of tuberculosis with one drug that breaks down the pathogen's protective barriers and ...
A solution to Darwin's 'mystery of the mysteries' emerges from the dark matter of the genome
Oct 26, 2009 |
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Biological species are often defined on the basis of reproductive isolation. Ever since Darwin pointed out his difficulty in explaining why crosses between two species often yield sterile or inviable progeny (for instance, ...
Synthetic gene circuit allows precise dosing of gene expression
Mar 10, 2009 |
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Researchers have crafted a gene circuit that permits precise tuning of a gene's expression in a cell, an advance that should allow for more accurate analysis of the gene's role in normal and abnormal cellular function.
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Subtle change dramatically reduces pathogenic potential of Huntington's protein
Dec 23, 2009 |
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Scientists have identified a key molecular switch that may drive the onset of Huntington's disease (HD), an incurable neurodegenerative disorder that leads to severe disruptions in muscle coordination and cognitive function. ...
Study shows immune system protein involved in reprogramming adult cells to express stem cell genes
Dec 22, 2009 |
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(PhysOrg.com) -- Scientists have discovered a protein required to quickly and efficiently reprogram human skin cells to express embryonic stem cell genes.
Genomes of identical twins reveal epigenetic changes that may play role in lupus
Dec 21, 2009 |
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Identical twins look the same and are nearly genetically identical, but environmental factors and the resulting cellular changes could cause disease in one sibling and not the other. In a study published online in Genome Re ...
Researchers create new 'smart' nanocapsule delivery system for use in protein therapy
Nanotechnology / Bio & Medicine
Dec 18, 2009 |
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the delivery of healthy proteins directly into human cells to replace malfunctioning proteins — is considered one of the most direct and safe approaches for treating diseases. But its effectiveness has been limited by low ...
Researchers design a tool to induce controlled suicide in human cells
Dec 17, 2009 |
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When cells accumulate excessive errors in the proteins they produce, apoptosis is activated, that is to say, a cell suicide programme; however, beforehand the cells attempt to rectify the problem through a number of rescue ...
Higher levels of protein hormone associated with lower risk of dementia, Alzheimer's disease
Dec 15, 2009 |
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Persons with higher levels of leptin, a protein hormone produced by fat cells and involved in the regulation of appetite, may have an associated reduced incidence of Alzheimer disease and dementia, according to a study in ...
Targeting brain cancer cell metabolism may provide new treatment
Dec 15, 2009 |
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Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according ...
Nanoprobes hit targets in tumors, could lessen chemo side effects
Nanotechnology / Bio & Medicine
Dec 14, 2009 |
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(PhysOrg.com) -- Tiny nanoprobes have shown to be effective in delivering cancer drugs more directly to tumor cells - mitigating the damage to nearby healthy cells - and Purdue University research has shown that the nanoprobes ...
Researchers identify a scaffold regulating protein disposal
Dec 11, 2009 |
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How does a cell manage to identify and degrade the diverse types of defective proteins and thus protect the body against serious diseases? The researchers Sabine C. Horn, Professor Thomas Sommer, Professor Udo Heinemann and ...
RXR activation -- hope for new Parkinson's disease treatment
Medicine & Health / Neuroscience
Dec 11, 2009 |
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Following up on their previous work showing the rescue of dopamine neurons by chemicals that interact with the retinoid X receptor (RXR), researchers have now investigated the potential of these chemicals, known as RXR ligands, ...
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