News tagged with cellular pathway
Stress pathway identified as potential therapeutic target to prevent vision loss
A new study identifies specific cell-stress signaling pathways that link injury of the optic nerve with irreversible vision loss. The research, published by Cell Press in the February 9 issue of the journal Neuron, may le ...
Medicine & Health / Neuroscience
Feb 08, 2012 |
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Researchers discover key to immune cell's 'internal guidance' system
University of British Columbia researchers have discovered the molecular pathway that enables receptors inside immune cells to find, and flag, fragments of pathogens trying to invade a host.
Feb 05, 2012 |
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Researchers discover the processes leading to acute myeloid leukemia
Researchers at UC Santa Barbara have discovered a molecular pathway that may explain how a particularly deadly form of cancer develops. The discovery may lead to new cancer therapies that reprogram cells instead ...
Jan 30, 2012 |
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No more free rides for 'piggy-backing' viruses
Scientists have determined the structure of the enzyme endomannosidase, significantly advancing our understanding of how a group of devastating human viruses including HIV and Hepatitis C hijack human enzymes to reproduce ...
Jan 04, 2012 |
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Researchers examine role of inflammatory mechanisms in a healing heart
(Medical Xpress) -- Virginia Commonwealth University researchers have found that an inflammatory mechanism known as inflammasome may lead to more damage in the heart following injury such as a heart attack, pointing researchers ...
Medicine & Health / Cardiology
Nov 30, 2011 |
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Cell molecule identified as central player in the formation of new blood vessels
Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified a cellular protein that plays a central role in the formation of new blood vessels. The molecule is the protein ...
Nov 28, 2011 |
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How major signaling pathways are wired to our genome gives new insight into disease processes
Whitehead Institute scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. In this way, signaling pathways are targeted to genes that are most relevant to each ...
Oct 27, 2011 |
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Antineoplastic agents associated with thyroid dysfunction
Antineoplastic agents such as immunotherapies and targeted therapies that specifically target signaling pathways in cancer cells are associated with thyroid dysfunction in 20%-50% of cancer patients taking them, which can ...
Oct 18, 2011 |
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Growth hormone helps repair the zebrafish ear
Loud noise, especially repeated loud noise, is known to cause irreversible damage to the hair cells inside the cochlea and eventually lead to deafness. In mammals this is irreversible, however both birds and fish are able ...
Medicine & Health / Neuroscience
Sep 02, 2011 |
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Up from the depths: How bacteria capture carbon in the 'twilight zone'
Located between 200 and 1,000 meters below the ocean surface is a "twilight zone" where insufficient sunlight penetrates for microorganisms to perform photosynthesis. Details are now emerging about a microbial metabolic pathway ...
Sep 01, 2011 |
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Breast cancer tumor suppressor gene silenced by low O2
Low oxygen can silence the BRCA1 tumor suppressor gene and contribute to the progression of cancer, according to a paper in the August 2011 issue of the journal Molecular and Cellular Biology. Silencing this particular gene i ...
Aug 16, 2011 |
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New approach to link genome-wide association signals to biological function
Researchers have developed a new strategy to improve the outcome of genome-wide association (GWA) studies.
Jun 30, 2011 |
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Researchers find potential therapeutic target for controlling obesity
A new study from Mount Sinai School of Medicine has found that a cellular signaling pathway governs the differentiation of cells into fat tissue or smooth muscle, which lines the vascular system. Engaging this signaling pathway ...
Jun 14, 2011 |
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Once blamed for aging, ROS molecules may actually extend life
(Medical Xpress) -- In a new study, Yale University researchers have identified a pathway by which reactive oxygen species (ROS) molecules, which are usually implicated in the aging process due to their damage ...
Jun 08, 2011 |
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Genetics of melanoma chemoresistance
Malignant melanoma is a highly aggressive and notoriously chemoresistant form of cancer. In a new paper, Ohanna et al. reveal that anti-melanoma drugs may, paradoxically, induce a senescence-associated secretory profile ("secretome") ...
Jun 06, 2011 |
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