News tagged with cellular prion
'Good' prion-like proteins boost immune response
(Medical Xpress) -- A person's ability to battle viruses at the cellular level remarkably resembles the way deadly infectious agents called prions misfold and cluster native proteins to cause disease, UT Southwestern Medical ...
Aug 09, 2011 |
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Researchers find new piece in Alzheimer's puzzle
Yale researchers have filled in a missing gap on the molecular road map of Alzheimer's disease. In the Feb. 26 issue of the journal Nature, the Yale team reports that cellular prion proteins trigger the process by which ...
Feb 25, 2009 |
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Search results for cellular prion
Scientists identify most lethal known species of prion protein
Scientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in "mad cow" disease, but is at least 10 times more ...
Feb 09, 2012 |
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Medical researchers discover hidden side of prion diseases
Medical researchers in Canada and the United States recently published their joint findings that fatal prion diseases, which include BSE or "mad cow disease," have a hidden signature.
Nov 30, 2011 |
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Genetic screening in yeast reveals new candidate gene for Lou Gehrig's disease
(Medical Xpress) -- Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, is a universally fatal neurodegenerative disease. Mutations in two related proteins, TDP-43 and FUS, cause some forms of ALS. ...
Nov 15, 2011 |
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Screen finds an antidepressant, other drugs, opens possibility of treating brain-wasting mad cow disease
In a new study NYU School of Medicine researchers report that they have found several chemical compounds, including an antidepressant, that have powerful effects against brain-destroying prion infections in mice, opening ...
Sep 14, 2011 |
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Cellular stress can induce yeast to promote prion formation
It's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, ...
Jul 23, 2011 |
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Serum-free cultures help transplanted MSCs improve efficacy
Mensenchymal stem cells (MSCs), multipotent cells identified in bone marrow and other tissues, have been shown to be therapeutically effective in the immunosuppression of T-cells, the regeneration of blood vessels, assisting ...
Jun 28, 2011 |
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Into the (mis)fold: a diagnostic tool for proteins
(PhysOrg.com) -- Alzheimer’s disease is the most common form of dementia, currently affecting more than 35 million people worldwide. Although many genetic and hereditary factors are thought to contribute ...
Jun 01, 2011 |
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Errors in protein structure sparked evolution of biological complexity
Over four billion years of evolution, plants and animals grew far more complex than their single-celled ancestors. But a new comparison of proteins shared across species finds that complex organisms, including humans, have ...
May 18, 2011 |
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Studies of mutated protein in Lou Gehrig's disease reveal new paths for drug discovery
Several genes have been linked to ALS, with one of the most recent called FUS. Two new studies in PLoS Biology, one from the University of Pennsylvania School of Medicine, and the other from colleagues at Bra ...
Apr 26, 2011 |
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Mutant prions help cells foil harmful protein misfolding
Romping clumps of misfolded proteins are prime suspects in many neurological disorders including Alzheimer's, Parkinson's, and Creutzfeld-Jakob Disease. Those diseases are devastating and incurable, but a team of biologists ...
Mar 20, 2011 |
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List of search results for cellular prion
