News tagged with cellular senescence
Cellular senescence a double-edged sword
Biology /
Dec 03, 2008 |
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Scientists have identified a molecular cause behind the ravages of old age and in doing so have also shown how a natural process for fighting cancer in younger persons can actually promote cancer in older individuals. Cellular ...
Search results for cellular senescence
Preventing cancer without killing cells
Mar 30, 2007 |
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Inducing senescence in aged cells may be sufficient to guard against spontaneous cancer development, according to a paper published online this week in EMBO reports. It was previously unknown whether cellular senescence or ...
Enzyme for ubiquitin-dependent protein degradation linked to cellular senescence
Biology /
May 22, 2008 |
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A new study, published by Cell Press in the May 23rd issue of the journal Molecular Cell, identifies a pivotal role for the CUL7 E3 ubiquitin ligase in growth control. The research makes an exciting new connection betwee ...
Senescence in liver cells can provoke a beneficial immune reaction
Aug 21, 2008 |
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Although post-reproductive life in humans is often associated with decline and a loss of powers, an analogous state in certain cells -- called senescence -- is proving to be one of ironic potency. Scientists at Cold Spring ...
To protect against liver disease, body puts cells 'under arrest'
Aug 21, 2008 |
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A stable form of cell-cycle arrest known to offer potent protection against cancer also limits liver fibrosis, a condition characterized by an excess of fibrous tissue, according to a new report in the August 22nd Cell, a Cell ...
Blocking beta1-integrin to treat cancer
Jun 06, 2007 |
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Targeting the function of a protein known as beta1-integrin might represent a novel approach to cancer treatment, according to a paper published online in The EMBO Journal this week. Blocking the action of this protein could ...
DNA damage response confers a barrier for viral tumorigenesis
Sep 28, 2007 |
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Kaposi’s sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi’s sarcoma (KS). KSHV infection is endemic in sub-Saharan Africa where KS is nowadays the most common malignancy, due to widespread ...
Study shows that some malignant tumors can be shut down after all
Nov 09, 2009 |
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Oncologists have had their hands tied because more than half of all human cancers have mutations that disable a protein called p53. As a critical anti-cancer watchdog, p53 masterminds several cancer-fighting operations within ...
Escape cancer, but age sooner? The dark side of the tumor suppressing process
Biology /
Dec 02, 2008 |
4.8 / 5 (17) |
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Cells shut down and stop dividing when their DNA is damaged, in a process known as cellular senescence, so as to prevent damaged DNA from leading to unregulated cell division and therefore cancer. However, a new study, published ...
Researchers identify gene that helps plant cells keep communication channels open
Biology /
Feb 17, 2009 |
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Plant cells communicate via microscopic channels called plasmodesmata that are embedded in their cell walls. For the stem cells in the plants' growing tips, called "meristems," the plasmodesmata are lifelines, allowing nutrients ...
Keeping cells youthful: How telomere-building proteins get drawn into the fold
Biology /
Aug 25, 2008 |
4.6 / 5 (13) |
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It may take just one or two proteins to polish off a simple cellular task, but life-or-death matters, such as caring for the ends of chromosomes known as telomeres, require interacting crews of proteins, all with a common ...
List of search results for cellular senescence
